Pro-Oxidant Activity

A neuropeptide with diverse biological activities

6α-hydroxy Cholesterol is an oxysterol that increases superoxide anion production in SK-N-BE cells when used at concentrations of 50 and 100 μM.

4-hydroxy Alternariol is a metabolite of the mycotoxin alternariol formed through cytochrome P450 (CYP450) metabolism.

AAPH is a water-soluble azo compound

Ermanin es un flavonoide aislado de Tanacetum microphyllum.

El acetato de metilprednisolona, un derivado de la prednisolona, es una hormona corticosteroide.

SRS11-92, un anÁlogo de Ferrostatin-1 (Fer-1), es un potente inhibidor de la ferroptosis.

10-methyl-9-(phenoxycarbonyl) Acridinium is an acridinium ester that produces fluorescent 10-methyl-9-acridone upon oxidation with hydrogen peroxide, persulfates, and other oxidants in alkaline conditions.

La 1-palmitoil-2-hidroxi-sn-glicero-3-PC es una abundante LPC gonadal (lisofosfatidilcolina).

Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (H2O2), as it oxidizes specific substrates in the presence of water and oxygen.

9,10-Anthracenediyl-bis(methylene)dimalonic Acid es un derivado soluble en agua del antraceno y se aplica generalmente como sonda de oxígeno singlet. 9,10-Anthracenediyl-bis(methylene)dimalonic Acid puede ser fotoblanqueado por oxígeno singlete a su endoperóxido correspondiente, causando una disminución dependiente del tiempo en la absorbancia a 380-400nm

AEM1 es un inhibidor de Nrf2. AEM1 reduce las expresiones de genes dependientes de Nrf2 en células A549 e inhibe el crecimiento de células A549 in vitro e in vivo.

Erastin2 es un potente inhibidor del sistema xc y agente inductor de ferroptosis.

L-Selenocystine es el producto de oxidación diselenuro de la selenocisteína, y posee una marcada capacidad antioxidante.

MGR2 is a negative control compound for the activity of the reactive oxygen species-generating probe MGR1.

Formado in vivo por la reacción de NO con superóxido.

Superoxide radical anion is a toxic by-product of mitochondrial respiration that is formed from approximately 1-4% of the oxygen metabolized by aerobic organisms.

Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol.

Urotensin II is a somatostatin-like neuropeptide agonist of the urotensin II receptor (UTR; Ki = 2 nM).

β-BHC is an isomer of the organochlorine pesticide γ-lindane that is a potential impurity found in commercial preparations of lindane.

A trichothecene mycotoxin