Radulone A is a sesquiterpene fungal metabolite originally isolated from R. confluens that has diverse biological activities. It is active against eight bacterial strains (MICs = 41-406 µM). Radulone A inhibits ADP-, collagen-, arachidonic acid-, or phorbol 12-myristate 13-acetate-induced aggregation of isolated human platelets (IC50 = 2, 28, 53, and 38 µM, respectively). It induces cytotoxicity in L1210 skin lymphocytic leukemia, HL-60 promyeoloblast leukemia, and HeLa cervical cancer cells and COS-7 kidney fibroblasts (IC50s = 1, 2, 20, and 16 µM).
Radulone A
Catalog No.: GC92256Purity:>70.00%
Radulone A is a sesquiterpene fungal metabolite originally isolated from R. confluens that has diverse biological activities.
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Cas No.: 221374-79-4
1mgIn Stock
$245.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $245.00 | In Stock | 1 |
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Citas (Citations)
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Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Descripción (Description)
Documentos del producto (Product Documents)
Purity:>70.00%Appearance:A solid
Propiedades químicas (Chemical Properties)
N.º CAS
221374-79-4
Nombre químico
(3S,8aS,8bS,9S)-2,3,8,8a-tetrahydro-9-hydroxy-3,6,8a-trimethyl-3,8b-methano-8bH-cyclobuta[5,6]benzo[1,2-b]pyran-5(7H)-one
SMILES
CC(C1=O)=C2CC[C@]2(C)[C@@]34OC[C@](C)(C=C14)[C@@H]3O
Fórmula molecular
C15H18O3
Peso molecular
246.30162
Solubilidad
Dichloromethane: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
Almacenamiento
-20°C
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.
Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad
g/mol
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