Transcription Factors
Products Related to Transcription Factors(118)
- GC44459N-pentadecanoyl-L-Homoserine lactoneCAS: 182359-66-6Purity: >98.00%
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.
- GC44652PK7242 (maleate)Purity: >95.00%
The protein p53, often called the 'guardian of the genome,' is a transcription factor that is activated in response to cellular stress (low oxygen levels, heat shock, DNA damage, etc.) and acts to prevent further proliferation of the stressed cell by promoting cell cycle arrest or apoptosis.
- GC44943sPLA2 InhibitorCAS: 393569-31-8Purity: >95.00%
El inhibidor de sPLA2, un derivado de D-tirosina, es un potente inhibidor de la fosfolipasa A2 secretora (sPLA2) activo por vÍa oral con una IC50 de 29 nM para la isoforma IIa de PLA2 secretora no pancreÁtica humana (hnpsPLA2-IIa).
- GC44984TAF 10 PeptidePurity: >98.00%
TAF10 is one of many protein factors or coactivators associated with RNA polymerase II activity.
- GC45186ZLN005 (hydrochloride)Purity: >98.00%
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis.
- GC45640TP-238 (hydrochloride)CAS: 2415263-05-5Purity: >99.00%
TP-238 (clorhidrato) es una sonda CECR2/BPTF dual potente y selectiva con valores IC50 de 30 nM y 350 nM, respectivamente. TP-238 (clorhidrato) también inhibe BRD9 con un pIC50 de 5,9 y es menos activo frente a otras 338 quinasas.
- GC45768Pranlukast-d4CAS: 2713172-43-9Purity: >99.00%
A neuropeptide with diverse biological activities
- GC45965Tolfenamic Acid-d4CAS: 1246820-82-5Purity: >99.00%
An internal standard for the quantification of tolfenamic acid
- GC46148Filgotinib-d4CAS: 2041095-50-3Purity: >99.00%
Filgotinib-d4 (GLPG0634-d4) es el Filgotinib marcado con deuterio. Filgotinib (GLPG0634) es un inhibidor selectivo de JAK1 con IC50 de 10 nM, 28 nM, 810 nM y 116 nM para JAK1, JAK2, JAK3 y TYK2, respectivamente.
- GC46347(S)-(+)-MethopreneCAS: 65733-16-6Purity: >95.00%
El (S)-metopreno es un análogo de la hormona juvenil que impide que el insecto cambie de pupa a adulto y se usa como insecticida.
- GC465032-NPCAS: 65182-56-1Purity: >99.50%
El 2-(1,8-naftiridin-2-il)fenol es un potenciador selectivo de la transcripciÓn de STAT1. 2-(1,8-naftiridin-2-il)fenol puede mejorar la capacidad de IFN-γ para inhibir la proliferaciÓn de células de cÁncer de mama humano y fibrosarcoma.
- GC465532-Nonylquinolin-4(1H)-oneCAS: 55396-45-7Purity: >95.00%
A quinolone alkaloid with diverse biological activities
- GC466734-octynyl ItaconateCAS: 2454181-83-8Purity: >98.00%
El itaconato de 4 octinilo (ITalk) es una sonda bioortogonal especÍfica para la elaboraciÓn de perfiles quimioproteÓmicos cuantitativos y especÍficos del sitio de Itaconation en células vivas.
- GC46862Apigenin-d5CAS: 263711-74-6Purity: >99.00%
An internal standard for the quantification of apigenin
- GC47456Indole-3-pyruvic AcidCAS: 392-12-1Purity: >97.00%
El Ácido indol-3-pirÚvico, un cetoanÁlogo del triptÓfano, es un agonista de AHR activo por vÍa oral.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC44459 | N-pentadecanoyl-L-Homoserine lactone | 182359-66-6 | >98.00% | |
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. | ||||
| GC44652 | PK7242 (maleate) | - | >95.00% | |
The protein p53, often called the 'guardian of the genome,' is a transcription factor that is activated in response to cellular stress (low oxygen levels, heat shock, DNA damage, etc.) and acts to prevent further proliferation of the stressed cell by promoting cell cycle arrest or apoptosis. | ||||
| GC44888 | SI-2 | 380537-35-9 | >99.50% | |
SI-2 is an inhibitor of steroid receptor coactivator 3 (SRC-3). | ||||
| GC44943 | sPLA2 Inhibitor | 393569-31-8 | >95.00% | |
El inhibidor de sPLA2, un derivado de D-tirosina, es un potente inhibidor de la fosfolipasa A2 secretora (sPLA2) activo por vÍa oral con una IC50 de 29 nM para la isoforma IIa de PLA2 secretora no pancreÁtica humana (hnpsPLA2-IIa). | ||||
| GC44984 | TAF 10 Peptide | - | >98.00% | |
TAF10 is one of many protein factors or coactivators associated with RNA polymerase II activity. | ||||
| GC45186 | ZLN005 (hydrochloride) | - | >98.00% | |
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis. | ||||
| GC45503 | L-Moses (hydrochloride) | - | >98.00% | |
| ||||
| GC45640 | TP-238 (hydrochloride) | 2415263-05-5 | >99.00% | |
TP-238 (clorhidrato) es una sonda CECR2/BPTF dual potente y selectiva con valores IC50 de 30 nM y 350 nM, respectivamente. TP-238 (clorhidrato) también inhibe BRD9 con un pIC50 de 5,9 y es menos activo frente a otras 338 quinasas. | ||||
| GC45764 | Ciclopirox-d11 (sodium salt) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45768 | Pranlukast-d4 | 2713172-43-9 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45820 | Balsalazide-d4 | - | >99.00% | |
La balsalazida-d4 es balsalazida marcada con deuterio. | ||||
| GC45894 | Daunorubicin-13C-d3 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45921 | (±)8(9)-EET-d11 methyl ester | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45960 | 9c(i472) | 2349374-37-2 | >95.00% | |
9c(i472) es un potente inhibidor de 15-LOX-1 (15-lipoxigenasa-1) con un valor IC50 de 0,19 μM. | ||||
| GC45965 | Tolfenamic Acid-d4 | 1246820-82-5 | >99.00% | |
An internal standard for the quantification of tolfenamic acid | ||||
| GC46148 | Filgotinib-d4 | 2041095-50-3 | >99.00% | |
Filgotinib-d4 (GLPG0634-d4) es el Filgotinib marcado con deuterio. Filgotinib (GLPG0634) es un inhibidor selectivo de JAK1 con IC50 de 10 nM, 28 nM, 810 nM y 116 nM para JAK1, JAK2, JAK3 y TYK2, respectivamente. | ||||
| GC46264 | (±)8(9)-EET-d11 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46347 | (S)-(+)-Methoprene | 65733-16-6 | >95.00% | |
El (S)-metopreno es un análogo de la hormona juvenil que impide que el insecto cambie de pupa a adulto y se usa como insecticida. | ||||
| GC46503 | 2-NP | 65182-56-1 | >99.50% | |
El 2-(1,8-naftiridin-2-il)fenol es un potenciador selectivo de la transcripciÓn de STAT1. 2-(1,8-naftiridin-2-il)fenol puede mejorar la capacidad de IFN-γ para inhibir la proliferaciÓn de células de cÁncer de mama humano y fibrosarcoma. | ||||
| GC46553 | 2-Nonylquinolin-4(1H)-one | 55396-45-7 | >95.00% | |
A quinolone alkaloid with diverse biological activities | ||||
| GC46673 | 4-octynyl Itaconate | 2454181-83-8 | >98.00% | |
El itaconato de 4 octinilo (ITalk) es una sonda bioortogonal especÍfica para la elaboraciÓn de perfiles quimioproteÓmicos cuantitativos y especÍficos del sitio de Itaconation en células vivas. | ||||
| GC46862 | Apigenin-d5 | 263711-74-6 | >99.00% | |
An internal standard for the quantification of apigenin | ||||
| GC47435 | HPI-1 (hydrate) | - | >95.00% | |
A Hedgehog pathway inhibitor | ||||
| GC47456 | Indole-3-pyruvic Acid | 392-12-1 | >97.00% | |
El Ácido indol-3-pirÚvico, un cetoanÁlogo del triptÓfano, es un agonista de AHR activo por vÍa oral. | ||||
