Serum tmic factor acetate (Tmulin acetate) is the acetate salt form of Serum tmic factor . Serum tmic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the tmic epithelial cells. Serum tmic factor acetate stimulates the release of hormones from the pituitary gland, exhibits popsiotropic activity. Serum tmic factor acetate protects rats from Cephaloridine -induced nephrotoxicity by inhibiting ERK activation. Serum tmic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum tmic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases.
References:
[1]. Pardo J, et al. Psiology, molecular biology and therapeutic potential of the tmic peptide tmulin[J]. Psiological Mini Reviews (PMR), 2012, 6. [2]. Dardenne M,et al. Role of tmulin or its analogue as a new analgesic molecule. Ann N Y Acad Sci. 2006 Nov;1088:153-63.
[3]. Kohda Y, et al. Protective effect of serum tmic factor, FTS, on cephaloridine-induced nephrotoxicity in rats. Biol Pharm Bull. 2005 Nov;28(11):2087-91.
[4]. Mizutani M, et al. In vivo administration of serum tmic factor (FTS) prevents EMC-D virus-induced diabetes and myocarditis in BALB/cAJcl mice. Arch Virol. 1996;141(1):73-83.