GLPBio

SR-4554

Catalog No.: GC79900Purity:>98.50%
COASDSData Sheet
SR-4554 is a probe for the measurement of tumor hypoxia.

Los productos son exclusivamente para uso en investigación. No aptos para uso humano. No vendemos a pacientes.

SR-4554
Cas No.: 167648-73-9
10mM (in 1mL DMSO)In Stock
$396.00
1
1mgIn Stock
$180.00
1
5mgIn Stock
$360.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citas (Citations)

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Descripción (Description)

SR-4554 is a probe for the measurement of tumor hypoxia. SR-4554 undergoes enzymatic single-electron reduction reactions within hypoxic cells. SR-4554 determines the 19 F retention index for four commonly used mouse tumors (EMT6, SCCVII, KILT and RIF-I) through 19 F MRS technique. SR-4554 can used to detect tumor Hypoxia noninvasively by 19 F magnetic resonance spectroscopy ( 19 F MRS) [1].

References:
[1]. Aboagye EO, et al. Preclinical evaluation of the fluorinated 2-nitroimidazole N-(2-hydroxy-3,3,3-trifluoropropyl)-2-(2-nitro-1-imidazolyl) acetamide (SR-4554) as a probe for the measurement of tumor hypoxia. Cancer Res. 1997 Aug 1;57(15):3314-8.

Documentos del producto (Product Documents)

Purity:>98.50%Appearance:A solid
COASDSData Sheet

Propiedades químicas (Chemical Properties)

N.º CAS
167648-73-9
Fórmula molecular
C8H9F3N4O4
Peso molecular
282.18
Solubilidad
DMSO: ≥ 100 mg/mL (354.38 mM)
Almacenamiento
Store at -20°C, sealed storage, away from moisture and light
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.

Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad

g/mol

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