SSTC3 |
| Catalog No.GC39637 |
SSTC3 es un activador de caseÍna quinasa 1α (CK1α) (Kd = 32 nM) que inhibe la seÑalizaciÓn de WNT (EC50 = 30 nM). SSTC3 presenta una toxicidad gastrointestinal mÍnima en comparaciÓn con otras clases de inhibidores de WNT.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1242422-09-8
Sample solution is provided at 25 µL, 10mM.
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SSTC3 is a casein kinase 1α (CK1α) activator (Kd = 32 nM) that inhibits WNT signaling (EC50 = 30 nM). SSTC3 exhibits minimal gastrointestinal toxicity compared to other classes of WNT inhibitors[1].
[1]. Li B, et al, Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors. Sci Signal. 2017 Jun 27;10(485). pii: eaak9916.
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
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