GLPBio

ZX-J-19L

Catalog No.: GC79367Purity:>99.00%
ZX-J-19L is a CyPJ inhibitor with inhibitory activity against a variety of tumor cell lines.

Los productos son exclusivamente para uso en investigación. No aptos para uso humano. No vendemos a pacientes.


ZX-J-19L
Cas No.: 1346754-06-0
10mM (in 1mL DMSO)In Stock
$84.00
1
5mgIn Stock
$77.00
1
10mgIn Stock
$122.00
1
25mgIn Stock
$230.00
1
50mgIn Stock
$367.00
1

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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    31, 1291–1307 (2021)

Descripción (Description)

ZX-J-19L is a CyPJ inhibitor with inhibitory activity against a variety of tumor cell lines. ZX-J-19L inhibits the growth of human liver cancer cells, human breast cancer cells, ovarian cancer cells and prostate cancer cells in vitro. ZX-J-19L can be used for tumor research [1].

In Vitro, ZX-J-19L (1.0-250 µM; 48 h) inhibits the proliferation of human hepatocellular carcinoma SK-HEP1 and QGY cells[1]. ZX-J-19L (20 µM; 48 h) inhibits the growth of human breast cancer (HCC1954, BT474, MDA-MB468), ovarian cancer (SKOV3) and prostate cancer (PC3, LNCaP) cells[1].

References:
[1]. Zhao X, et al. Cyclophilin J PPIase Inhibitors Derived from 2,3-Quinoxaline-6 Amine Exhibit Antitumor Activity. Front Pharmacol. 2018;9:126. Published 2018 Feb 21.

Documentos del producto (Product Documents)

Purity:>99.00%Appearance:A solid

Propiedades químicas (Chemical Properties)

N.º CAS
1346754-06-0
Fórmula molecular
C24H21N3O
Peso molecular
367.44
Solubilidad
DMSO: 100 mg/mL (272.15 mM; Need ultrasonic)
Almacenamiento
Store at -20°C
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.

Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad

g/mol

Reviews

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