GLPBio

Stemoninine

Catalog No.: GC77604
Stemoninine is a lycoris alkaloid that can be used as an antitussive. Stemoninine has significant inhibitory activity against human acetylcholinesterase (AChE) (IC50=5.52 μM).

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Stemoninine
Cas No.: 69772-72-1
1mgIn Stock
$720.00
1

Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Stemoninine is a lycoris alkaloid that can be used as an antitussive. Stemoninine has significant inhibitory activity against human acetylcholinesterase (AChE) (IC50=5.52 μM).

References:
[1].Peixi Bi, et al. Method of making antitussive medicine and relieving cough. CN1931171A. 2006-09-12
[2].Ramli, et al. "Alkaloids from the roots and leaves of Stichoneuron halabalensis and their acetylcholinesterase inhibitory activities." Natural Product Communications 8.6 (2013): 1934578X1300800603.

Product Documents

Appearance:A solid

Chemical Properties

CAS No.
69772-72-1
SMILES
CC[C@@H]1[C@](C=C2C)(OC2=O)O[C@@](CCC3)([H])[C@@]1([H])[C@@]4([H])N3[C@@]([C@](OC5=O)([H])C[C@@H]5C)([H])CC4
Molecular Formula
C22H31NO5
Molecular Weight
389.49
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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