TLN-232, also known as CAP-232, is a synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may disrupt tumor cell anaerobic glycolysis. M2PK is a dimeric isoform of PK and the predominant PK isoform found in tumor cells.
TLN-232
Catalog No.: GB62175Purity:>98.00%Synonyms: TLN232; TLN 232; TLN232; CAP232; CAP232; CAP 232. Amino acid sequence: DPheCysDTrpLysCysThrNH2.
TLN-232, also known as CAP-232, is a synthetic cyclic heptapeptide with potential antineoplastic activity.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 158899-10-6
5mgIn Stock
$190.00
1
10mgIn Stock
$350.00
1
25mgIn Stock
$550.00
1
50mgIn Stock
$950.00
1
100mgIn Stock
$1,650.00
1
200mgIn Stock
$2,850.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 5mg | $190.00 | In Stock | 1 | |
| 10mg | $350.00 | In Stock | 1 | |
| 25mg | $550.00 | In Stock | 1 | |
| 50mg | $950.00 | In Stock | 1 | |
| 100mg | $1,650.00 | In Stock | 1 | |
| 200mg | $2,850.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
158899-10-6
Synonyms
TLN232; TLN 232; TLN232; CAP232; CAP232; CAP 232. Amino acid sequence: DPheCysDTrpLysCysThrNH2.
SMILES
O=C([C@@H](NC([C@H](CCCCN)NC([C@@H](CC1=CNC2=C1C=CC=C2)N3)=O)=O)CSSC[C@H](NC([C@H](N)CC4=CC=CC=C4)=O)C3=O)N[C@@H]([C@H](O)C)C(N)=O
Molecular Formula
C36H49N9O7S2
Molecular Weight
783.96
Solubility
Soluble in DMSO, not in water
Storage
Store at-20℃
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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