GLPBio

TRS-005

Catalog No.: GC78787Purity:>99.50%
TRS-005 is an anti- CD20 ADC, formed by conjugating an anti-CD20 monoclonal antibody to MMAE via a Val-Cit linker.

Products are for research use only. Not for human use. We do not sell to patients.


TRS-005
1mgIn Stock
$292.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

TRS-005 is an anti- CD20 ADC, formed by conjugating an anti-CD20 monoclonal antibody to MMAE via a Val-Cit linker. TRS-005 targets CD20-positive tumor cells and delivers MMAE into cells through receptor-mediated endocytosis. TRS-005 can be used for research on relapsed/refractory B-cell non-Hodgkin lymphoma (specifically diffuse large B-cell lymphoma ) [1].

References:
[1]. Shi Y, et al. The anti-CD20 antibody-drug conjugates TRS005 in relapse/refractory CD20-positive B-cell non-Hodgkin lymphoma: A multicenter, open-label, single-arm, phase I study[J]. 2024.

Product Documents

Purity:>99.50%Appearance:A liquid

Chemical Properties

Storage
Store at -80°C, protect from light
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion

g/mol

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