VU533 (APE-PLD) activator is a potent NAPE-PLD activator with an EC50 value of 0.30 µM. NAPE-PLD activator (VU533) can enhance NAPE-PLD activity and increase efferocytosis by macrophages. NAPE-PLD activator (VU533) can be used for cardiometabolic diseases research.
References:
[1]. Zarrow JE, et al. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. ACS Chem Biol. 2023 Aug 18;18(8):1891-1904.
VU533
Catalog No.: GC71354Purity:>99.00%
VU533 (APE-PLD) activator is a potent NAPE-PLD activator with an EC50 value of 0.30 µM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 923417-09-8
5 mgIn Stock
$113.00
1
10 mgIn Stock
$180.00
1
25 mgIn Stock
$360.00
1
50 mgIn Stock
$585.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 5 mg | $113.00 | In Stock | 1 | |
| 10 mg | $180.00 | In Stock | 1 | |
| 25 mg | $360.00 | In Stock | 1 | |
| 50 mg | $585.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>99.00%Appearance:A solid
Chemical Properties
CAS No.
923417-09-8
Molecular Formula
C21H22FN3O3S2
Molecular Weight
447.55
Solubility
DMSO : 125 mg/mL (279.30 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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