GLPBio

Zoniporide

Catalog No.: GC72779Purity:>99.00%Synonyms: CP-597396
Zoniporide (CP-597396) is a potent and selective NHE-1 inhibitor with cardioprotective activity.

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Zoniporide
Cas No.: 241800-98-6
5 mgIn Stock
$152.00
1
10 mgIn Stock
$246.00
1
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Citations

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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    35, 97–116 (2025)
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    31, 1291–1307 (2021)

Description

Zoniporide (CP-597396) is a potent and selective NHE-1 inhibitor with cardioprotective activity. Zoniporide inhibits 22Na+ uptake by human NHE-1-expressing fibroblasts in a concentration-dependent manner (IC50=14 nM). Zoniporide inhibits platelet swelling in vitro with an IC50 of 0.059 μM. Zoniporide can be used in the study of cardiovascular disease.

References:
[1]. Marala, et al. Zoniporide: a potent and highly selective inhibitor of human Na+/H+ exchanger-1. European journal of pharmacology 451.1 (2002): 37-41.

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Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
241800-98-6
Synonyms
CP-597396
Molecular Formula
C17H16N6O
Molecular Weight
320.35
Solubility
DMSO : 125 mg/mL (390.20 mM; Need ultrasonic)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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