GLPBio

1'-epi Gemcitabine hydrochloride

Catalog No.: GC74183Purity:>98.00%Synonyms: 1'-epi LY 188011 hydrochloride
COASDSData Sheet
1'-epi Gemcitabine drochloride is the isomer of Gemcitabine drochloride , and can be used as an experimental control.

Products are for research use only. Not for human use. We do not sell to patients.

1'-epi Gemcitabine hydrochloride
Cas No.: 122111-05-1
1 mgIn Stock
$208.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

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Description

1'-epi Gemcitabine drochloride is the isomer of Gemcitabine drochloride , and can be used as an experimental control. Gemcitabine drochloride (LY 188011 drochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine drochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis.

References:
[1]. Yip-Schneider MT, et al. Dimetlaminoparthenolide and Gemcitabine: a survival study using a genetically engineered mouse model of pancreatic cancer. BMC Cancer. 2013 Apr 17;13:194.
[2]. Lou M, et al. Psical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy. J Biol Chem. 2017 Jun 2;292(22):9136-9149.
[3]. Gagnadoux F, et al. Safety of pulmonary administration of gemcitabine in rats. J Aerosol Med. 2005 Summer;18(2):198-206
[4]. Wang H, et al. Enhanced efficacy of Gemcitabine by indole-3-carbinol in pancreatic cell lines: the role of human equilibrativenucleoside transporter 1. Anticancer Res. 2011 Oct;31(10):3171-80

Product Documents

Purity:>98.00%Appearance:A liquid
COASDSData Sheet

Chemical Properties

CAS No.
122111-05-1
Synonyms
1'-epi LY 188011 hydrochloride
Molecular Formula
C9H12ClF2N3O4
Molecular Weight
299.66
Storage
-20°C, sealed storage, away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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