1-Aminodecylidene bis-phosphonic acid is a potent inhibitor of acid sphingomyelinase (IC50 = 20 nM). It is selective for acid sphingomyelinase over neutral sphingomyelinase (IC50 = >100 μM). 1-Aminodecylidene bis-phosphonic acid completely inhibits apoptosis induced by dexamethasone in HepG2 cells.
1-Aminodecylidene bis-Phosphonic Acid
Catalog No.: GC41985Purity:>95.00%Synonyms: 1-Amindecane-1,1-Diphosphonic Acid; ARC 39
1-Aminodecylidene bis-phosphonic acid is a potent inhibitor of acid sphingomyelinase (IC50 = 20 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 15049-93-1
1mgIn Stock
$143.00
1
5mgIn Stock
$528.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $143.00 | In Stock | 1 | |
| 5mg | $528.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>95.00%Appearance:A solid
Chemical Properties
CAS No.
15049-93-1
Synonyms
1-Amindecane-1,1-Diphosphonic Acid; ARC 39
SMILES
NC(CCCCCCCCC)(P(O)(O)=O)P(O)(O)=O
Molecular Formula
C10H25NO6P2
Molecular Weight
317.3
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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