1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE) is a phospholipid that contains palmitic acid and oleic acid at the sn-1 and sn-2 positions, respectively.1 It is a major component of E. coli lipid bilayers, and vesicles composed of 1,2-POPE can be disrupted by polycationic antimicrobials.1,2 1,2-POPE has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for spleen- and liver-specific targeting in mice.3
Citations
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Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
26662-94-2
Molecular Formula
C39H76NO8P
Molecular Weight
718
Solubility
Chloroform: 100 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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