Lipid-Based Drug Delivery

Lysophosphatidylcholines is an important class of phospholipid molecules, which are the products of phosphatidylcholine hydrolysis by phospholipase A2.

1,2-Dihexadecyl-sn-glycero-3-PC is a synthetic ether-linked phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions.

1,2-Dierucoyl-sn-glycero-3-PC (DEPC) is the composition of liposome membrane.

DODAP (1,2-Dioleoyl-3-dimethylammonium-propane) is a cationic lipid used as the lipid nanoparticle (LNP) with the pKa value of 5.59.

Phosphatidylglycerols (sodium salt) is a phospholipid that is ubiquitous in almost all living organisms, with molecular structure features a negatively charged glycerol head group, which exists stably in the form of a sodium salt.

1,2-Dinonadecanoyl-sn-glycero-3-PC is a saturated phospholipid that has been used as a standard for the quantification of phosphatidylcholines in human synovial fluid.

1,2-Diphytanoyl-sn-glycero-3-PC is a phospholipid used to synthesize bilayer vesicles.

Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina.

Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2).

Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids.

Phosphatidylinositols (soy) (sodium salt) is a mixture of phosphatidylinositols.

1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid.

ALC-0159 is a non-ionic surfactant belonging to the class of PEGylated lipids. ALC-0159 can be used as a vaccine excipient.

Phosphatidic acid is a phospholipid and an intermediate in glycerolipid biosynthesis.

1,2-Diarachidoyl-sn-glycero-3-PC is a phospholipid containing the saturated long-chain (20:0) arachidic acid inserted at the sn-1 and sn-2 positions.

1-Stearoyl-2-myristoyl-sn-glycero-3-PC (SMPC) belongs to the class of asymmetric phospholipids, which have two chains of unequal length attached to the glycerol backbone.

1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.

1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated form of lysophosphatidylcholine (Lyso-PC).

Phosphatidylcholine species are a common class of phospholipids that comprise the mammalian cell membrane.

1,2-Diheptadecanoyl-sn-glycero-3-PC (DHDPC) is a synthetic phosphatidylcholine containing 17:0 fatty acids at the sn-1 and sn-2 positions.

1,2-Dihexanoyl-sn-glycero-3-PC (DHPC-C6) is a synthetic phosphatidylcholine containing the short-chain (6:0) caproic acid inserted at the sn-1 and sn-2 positions.

Phosphatidylethanolamines (PEs) are phospholipids found in biological membranes, serving both structural and functional roles.