14S(15R)-EET metl ester is an oxylipin and a cytochrome P450 metabolite of arachidonic acid .1 14S(15R)-EET metl ester binds to isolated guinea pig monocytes with a Ki value of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.2 It induces dilation of precontracted isolated canine epicardial arterioles (EC50 = 4 pM) and denuded porcine subepicardial arterioles (EC50 = 3 pM).3 Unlike 14R(15S)-EET, 14S(15R)-EET metl ester does not inhibit COX in enzyme assays or isolated platelets.4
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Product Documents
Purity:>95.00%Appearance:A solution in ethanol
Chemical Properties
CAS No.
110901-52-5
Molecular Formula
C21H34O3
Molecular Weight
334.5
Solubility
Ethanol: Soluble
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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