GLPBio

19S(20R)-EpDPA

Catalog No.: GC46476Purity:>98.00%Synonyms: 19S,20R-EDP, 19S,20R-EpDPE, 19S,20R-epoxy DPA, 19S,20R-epoxy Docosapentaenoic Acid
COASDSData Sheet
A neuropeptide with diverse biological activities

Products are for research use only. Not for human use. We do not sell to patients.

19S(20R)-EpDPA
Cas No.: 2460392-58-7
25 μgIn Stock
$63.00
1
50 μgIn Stock
$120.00
1
100 μgIn Stock
$224.00
1
500 μgIn Stock
$995.00
1
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Citations

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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    31, 1291–1307 (2021)

Description

19S(20R)-EpDPA is an oxylipin and a metabolite of docosahexaenoic acid .1,2 It is formed from DHA by various cytochrome P450 (CYP) isoforms in a stereoselective manner.2 Unlike 19R(20S)-EpDPA , 19S(20R)-EpDPA does not prevent calcium-induced increases in the spontaneous beating of isolated neonatal rat cardiomyocytes (NRCMs).3

1.Cinelli, M.A., Yang, J., Scharmen, A., et al.Enzymatic synthesis and chemical inversion provide both enantiomers of bioactive epoxydocosapentaenoic acidsJ. Lipid Res.59(11)2237-2252(2018) 2.Lucas, D., Goulitquer, S., Marienhagen, J., et al.Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450J. Lipid Res.51(5)1125-1133(2010) 3.Burke, J.E., and Dennis, E.A.Phospholipase A2 structure/function, mechanism, and signalingJ. Lipid Res.50(Suppl)S237-S242(2009)

Product Documents

Purity:>98.00%Appearance:A solution in ethanol
COASDSData Sheet

Chemical Properties

CAS No.
2460392-58-7
Synonyms
19S,20R-EDP, 19S,20R-EpDPE, 19S,20R-epoxy DPA, 19S,20R-epoxy Docosapentaenoic Acid
SMILES
CC[C@@H]1[C@@H](O1)C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O
Molecular Formula
C22H32O3
Molecular Weight
344.5
Solubility
Ethanol: soluble
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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