GLPBio

2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid

Catalog No.: GC81916Purity:>99.50%
COASDSData Sheet
2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid is a PROTACT linker and can be used for synthesis of P60-L3-VHL.

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2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid
Cas No.: 3036674-82-2
25mgIn Stock
$158.00
1
50mgIn Stock
$255.00
1
100mgIn Stock
$405.00
1
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    31, 1291–1307 (2021)

Description

2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid is a PROTACT linker and can be used for synthesis of P60-L3-VHL. 2-(2-(2-(6-Azidohexanamido)ethoxy)ethoxy)acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups [1].

References:
[1]. Yang B, et al. Discovery of a proteolysis targeting chimera (PROTAC) as a potent regulator of FOXP3. Bioorg Med Chem Lett. 2024 Nov 1;112:129945.

Product Documents

Purity:>99.50%Appearance:An oil
COASDSData Sheet

Chemical Properties

CAS No.
3036674-82-2
Molecular Formula
C12H22N4O5
Molecular Weight
302.33
Solubility
DMSO: 50 mg/mL (165.38 mM; Need ultrasonic)
Storage
Store at -20°C, stored under nitrogen, away from moisture
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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