GLPBio

2-(7-(Tert-butoxycarbonyl)-7-azaspiro[3.5]Nonan-2-yl)acetic acid

Catalog No.: GC81214Purity:>98.00%
COASDSData Sheet
2-(7-(Tert-butoxycarbonyl)-7-azaspiro[3.5]Nonan-2-yl)acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

Products are for research use only. Not for human use. We do not sell to patients.

2-(7-(Tert-butoxycarbonyl)-7-azaspiro[3.5]Nonan-2-yl)acetic acid
Cas No.: 1384265-35-3
100mgIn Stock
$89.00
1
250mgIn Stock
$152.00
1
500mgIn Stock
$237.00
1
1gIn Stock
$356.00
1
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Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

2-(7-(Tert-butoxycarbonyl)-7-azaspiro[3.5]Nonan-2-yl)acetic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

In Vitro, PROTACs contain two different ligands connected by a linker; one is a ligand for an E202 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1384265-35-3
Molecular Formula
C15H25NO4
Molecular Weight
283.37
Storage
Store at room temperature
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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