GLPBio

3-Hydroxyglutaric Acid dimethyl ester

Catalog No.: GC42290Purity:>98%Synonyms: Dimethyl 3-HG, Dimethyl β-HG, Dimethyl 3-hydroxyglutarate, Dimethyl 3-hydroxypentanedioate, 3-HG dimethyl ester, β-HG dimethyl ester, NSC 30047
3-Hydroxyglutaric acid dimethyl ester is a prochiral substrate and an esterified derivative of 3-hydroxyglutaric acid.

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3-Hydroxyglutaric Acid dimethyl ester
Cas No.: 7250-55-7
1gIn Stock
$40.00
1
5gIn Stock
$109.00
1
10gIn Stock
$197.00
1
25gIn Stock
$393.00
1

Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    31, 1291–1307 (2021)

Description

3-Hydroxyglutaric acid dimethyl ester is a prochiral substrate and an esterified derivative of 3-hydroxyglutaric acid . 3-Hydroxyglutaric acid dimethyl ester was used to characterize the ability of a lipase from C. antarctica to catalyze aminolysis of prochiral substrates, a process commonly utilized in the biosynthesis of statins.

Chemical Properties

CAS No.
7250-55-7
Synonyms
Dimethyl 3-HG, Dimethyl β-HG, Dimethyl 3-hydroxyglutarate, Dimethyl 3-hydroxypentanedioate, 3-HG dimethyl ester, β-HG dimethyl ester, NSC 30047
SMILES
O=C(CC(O)CC(OC)=O)OC
Molecular Formula
C7H12O5
Molecular Weight
176.2
Solubility
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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