GLPBio

5-Tert-butoxy-5-oxopentanoic acid

Catalog No.: GC81105Purity:>99.50%
COASDSData Sheet
5-Tert-butoxy-5-oxopentanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

Products are for research use only. Not for human use. We do not sell to patients.

5-Tert-butoxy-5-oxopentanoic acid
Cas No.: 63128-51-8
250mgIn Stock
$9.00
1
500mgIn Stock
$13.00
1
1gIn Stock
$18.00
1
5gIn Stock
$59.00
1
10gIn Stock
$99.00
1
25gIn Stock
$238.00
1
50gIn Stock
$393.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

5-Tert-butoxy-5-oxopentanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

In Vitro, PROTACs contain two different ligands connected by a linker; one is a ligand for an E418 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Product Documents

Purity:>99.50%Appearance:<17°C Solid,>17°C Liquid
COASDSData Sheet

Chemical Properties

CAS No.
63128-51-8
Molecular Formula
C9H16O4
Molecular Weight
188.22
Storage
Store at room temperature
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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