GLPBio

β-Endorphin, equine TFA

Catalog No.: GC72132Purity:>97.00%
β-Endorphin, equine TFA is an endogenous opioid peptide, which binds at high affinity to both μ/δ opioid receptors.

Products are for research use only. Not for human use. We do not sell to patients.


β-Endorphin, equine TFA
500 µgIn Stock
$81.00
1
1 mgIn Stock
$135.00
1
5 mgIn Stock
$315.00
1
10 mgIn Stock
$540.00
1

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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

β-Endorphin, equine TFA is an endogenous opioid peptide, which binds at high affinity to both μ/δ opioid receptors. β-Endorphin, equine TFA has analgesic properties.

β-Endorphin, equine TFA (0, 0.6, 1.2 and 3 μM) inhibits the striatal dopamine release[4].

β-Endorphin, equine TFA (2 or 20 μg/kg; i.p., once) effects the acquisition and retention in the rat[3].

References:
[1]. Yahav Dikshtein, et al. β-Endorphin via the Delta Opioid Receptor is a Major Factor in the Incubation of Cocaine Craving. Neuropsychopharmacology. 2013 Nov; 38(12): 2508-2514.
[2]. Niinistö KE, et al. Plasma levels of heat shock protein 72 (HSP72) and beta-endorphin as indicators of stress, pain and prognosis in horses with colic. Vet J. 2010 Apr;184(1):100-4.
[3]. Izquierdo I. Effects of a low and a high dose of beta-endorphin on acquisition and retention in the rat. Behav Neural Biol. 1980 Dec;30(4):460-4.
[4]. Loh HH, et al. beta-Endorphin in vitro inhibition of striatal dopamine release. Nature. 1976 Dec 9;264(5586):567-8.

Product Documents

Purity:>97.00%Appearance:A solid

Chemical Properties

Molecular Formula
C154H248N42O44S.xC2HF3O2
Molecular Weight
3423.94 (free acid)
Solubility
H2O : 100 mg/mL (Need ultrasonic)
Storage
Sealed storage, away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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