Endocrinology and Hormones

Endocrinology and Hormones
The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more
Products for Endocrinology and Hormones
- 5-alpha Reductase(8)
- Smoothened Receptors(3)
- Androgen Receptor(112)
- Aromatase(11)
- CRTH2(2)
- Estrogen/progestogen Receptor(129)
- GnRH(16)
- Opioid Receptor(127)
- RAAS(6)
- Thyroid hormone Receptor(53)
- ROR/RAR/RXR(72)
- FXR & LXR(61)
- Glucocorticoids & Mineralocorticoids(48)
- GPR(1)
- Cat.No. Product Name Information
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GC25832
Raloxifene
Raloxifene (Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women.
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GC25627
Menotropin
Menotropin (Human Menopausal Gonadotrophin) is a hormonally active medication for the treatment of fertility disturbances, which are extracted from the urine of postmenopausal women.
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GC25410
Fasiglifam (TAK-875)
Fasiglifam (TAK-875) is a selective GPR40 agonist with EC50 of 14 nM in human GPR40 expressing CHO cell line, 400-fold more potent than oleic acid.
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GC68427
GSK1521498 free base
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GC68337
Parathyroid hormone (1-34) (rat) acetate
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GC68212
Chenodeoxycholic acid-13C
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GC67956
Endomorphin 1 acetate
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GC67907
CCG258747
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GC67703
Adrenocorticotropic hormone TFA
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GC67698
Androgen receptor-IN-2
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GC52506
Ghrelin (human) (trifluoroacetate salt)
A growth hormone releasing peptide
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GC52494
β-Endorphin (rat) (trifluoroacetate salt)
An opioid neuropeptide
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GC52490
Glucagon (hydrochloride)
A peptide hormone
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GC52420
Drospirenone-13C3
An internal standard for the quantification of drospirenone
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GC52415
Angiotensin A (trifluoroacetate salt)
An AT1 and AT2 receptor agonist and active metabolite of angiotensin II
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GC52414
[Ala17]-MCH (trifluoroacetate salt)
An MCH-derived peptide and MCH receptor agonist
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GC52390
Spexin 1 (human, mouse, rat, bovine) (acetate)
An endogenous peptide and agonist of GAL2 and GAL3
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GC52388
[D-Lys3]-GHRP-6 (trifluoroacetate salt)
An antagonist of GHS-R1a
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GC52387
Crosstide (trifluoroacetate salt)
A peptide substrate for Akt
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GC52365
4-tert-Octylphenol monoethoxylate
An alkylphenolethoxylate and a degradation product of non-ionic surfactants
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GC52351
Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide
A biotinylated and citrullinated α-enolase peptide
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GC52329
Betamethasone-d5
An internal standard for the quantification of betamethasone
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GC52325
MeTC7
A vitamin D receptor antagonist
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GC52281
Losartan Azide
A potential impurity in commercial preparations of losartan
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GC52242
V-125
An RXR agonist
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GC66679
2,6-Dimethyl-L-tyrosine
2,6-Dimethyl-L-tyrosine (Dmt) is a tyrosine derivative that enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides.
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GC66433
Ro 41-5253
Ro 41-5253 is an orally active selective retinoic acid receptor alpha (RARα) antagonist. Ro 41-5253 can bind RARα without inducing transcription or affecting RAR/RXR heterodimerization and DNA binding. Ro 41-5253 can inhibit cancer cell proliferation and induce apoptosis, has antitumor activity.
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GC66207
Atraric acid
Atraric acid (Methyl atrarate) is a specific androgen receptor (AR) antagonist with anti-inflammatory and anticancer effects. Atraric acid represses the expression of the endogenous prostate specific antigen gene in both LNCaP and C4-2 cells. Atraric acid can also inhibit the synthesis of NO and cytokine, and suppress the MAPK-NFκB signaling pathway. Atraric acid can be used to research prostate diseases and inflammatory diseases.
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GC65936
Larsucosterol (trimethylamine)
Larsucosterol (DUR-928) trimethylamine, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol trimethylamine as a potent endogenous regulator decreases lipogenesis. Larsucosterol trimethylamine inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of SREBP-1.
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GC52189
Nomegestrol
Nomegestrol is a potent and orally available progestin, acts as a selective full progesterone receptor agonist, with a Kd of 5.44 nM for rat uterine progesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity.
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GC52185
(R,S)-Anatabine-d4
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GC52180
WAY-169916
WAY-169916 is a pathway-selective ligand of ER (estrogen receptor) that acts by inhibiting NF-kB transcriptional activity.
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GC52129
3-Amino-5-hydroxybenzoic Acid
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GC65587
CO23
CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation.
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GC65260
EDP-305
EDP-305 is an orally active, potent and selective farnesoid X receptor (FXR) agonist, with EC50 values of 34 nM (chimeric FXR in CHO cells) and 8 nM (full-length FXR in HEK cells).
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GC65255
Trestolone
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GC64854
Enzalutamide-d3
Enzalutamide D3 is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.
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GC64600
SK33
SK33, a trifluoromethylated enobosarm analog, is a potent, and tissue selective anti-androgen. SK33reduces androgen receptor (AR) transcriptional activity.
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GC64586
Nandrolone laurate
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GC64540
Ar-V7-IN-1
Ar-V7-IN-1 is a potent inhibitor of Ar-V7. AR-V7 is a hormone-independent splice variant of the androgen receptor. Ar-V7-IN-1 has the potential for the research of various indications, in particular cancers such as prostate cancer (extracted from patent WO2018114781A1, compound 43).
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GC52083
21-Deoxycortisone
A corticosteroid metabolite of 11-keto progesterone
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GC52043
Hydrocortisone Aceponate
Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid.
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GC52021
L-Thyroxine-N-methylamide
A potential impurity found in commercial preparations of L-thyroxine
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GC64301
DS08210767
DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.
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GC64147
Acetyl tetrapeptide-15
Acetyl tetrapeptide-15 is a synthetic peptide used in the cosmetics for sensitive skin.
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GC64007
(±)-U-50488 hydrate hydrochloride
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GC63935
Testosterone buciclate
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GC63932
Amsilarotene
Amsilarotene (TAC-101; Am 555S), an orally active synthetic retinoid, has selective affinity for retinoic acid receptor α (RAR-α) binding with Ki of 2.4, 400 nM for RAR-α and RAR-β. Amsilarotene induces the apoptotic of human gastric cancer, hepatocellular carcinoma and ovarian carcinoma cells. Amsilarotene can be used for the research of cancer.
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GC63884
Linzagolix
Linzagolix (KLH-2109; OBE-2109) is a potent, non-peptide, and orally active GnRH antagonist.
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GC49680
Clobetasone Propionate
A corticosteroid
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GC49679
Sauvagine (trifluoroacetate salt)
A neuropeptide hormone
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GC49676
6β-hydroxy Budesonide
A metabolite of budesonide
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GC49671
2,3-Oxidosqualene
An intermediate in the biosynthesis of sterols
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GC49654
BMS 270394
A RARγ agonist
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GC49653
Ramipril Diketopiperazine
A potential impurity found in commercial preparations of ramipril
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GC49648
Enobosarm-d4
An internal standard for the quantification of enobosarm
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GC49634
Isoflupredone
Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses.
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GC49631
Fluocortolone
A glucocorticoid
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GC49629
6β-hydroxy Prednisolone
A metabolite of prednisolone
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GC49611
21-Deoxycortisol-d8
An internal standard for the quantification of 21-deoxycortisol
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GC49609
2-bromo 17β-Estradiol
A synthetic steroid and inhibitor of estrogen 2-hydroxylase
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GC49592
Sermorelin (acetate)
A growth hormone-releasing hormone analog
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GC49574
Somatostatin-28 (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
A cyclic neuropeptide hormone
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GC49563
Fenhexamid
Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor.
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GC49562
4-methoxy Estrone
An active metabolite of estrone
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GC49542
5α-Androstan-3β-ol
A steroidal androgen
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GC49520
(S)-Equol
An estrogen receptor β agonist
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GC49475
Triptorelin (trifluoroacetate salt)
A synthetic GNRH peptide agonist
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GC49459
Desmopressin (trifluoroacetate salt)
A vasopressin receptor agonist
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GC63764
7-α-Methylthio Spironolactone-D3
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GC63755
Exemestane-D2
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GC63686
Naloxone methiodide
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GC63595
NH-3
NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM.
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GC63579
Linuron
Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards.
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GC63431
DPDPE TFA
DPDPE TFA, an opioid peptide, is a selective δ-opioid receptor?(DOR) agonist?with anticonvulsant effects.
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GC63402
Rezvilutamide
Rezvilutamide (SHR3680) is an androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer.
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GC63292
(rac)-PF-998425
(Rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist.
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GC63217
Testosterone undecanoate
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GC63200
Spiradoline
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GC63115
Nociceptin (1-13), amide TFA
Nociceptin (1-13), amide TFA is a potent ORL1 receptor (opioid receptor-like 1 receptor, OP4) agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes.
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GC63096
Nandrolone phenylpropionate
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GC63072
Methyl-6-alpha-Naltrexol
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GC63066
Methenolone acetate
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GC62992
Glutaurine
Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid.
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GC62761
1α-Hydroxy-3-epi-vitamin D3
1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion.
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GC49427
3,5-Diiodo-L-thyronine
3,5-Diiodo-L-thyronine is an endogenous metabolite.
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GC49423
Metanephrine-d3 (hydrochloride)
An internal standard for the quantification of metanephrine
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GC49408
Ramipril Diketopiperazine Acid
A potential impurity found in commercial preparations of ramipril
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GC49399
N-Desbutyl Dronedarone (hydrochloride)
Debutyldronedarone (SR35021) hydrochloride, the main metabolite of Dronedarone, is a selective thyroid hormone receptor α1 (TRα1) inhibitor.
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GC49393
all-trans-13,14-Dihydroretinol
A metabolite of all-trans retinoic acid
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GC49391
7α-Thiospironolactone
An active metabolite of spironolactone
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GC49389
Tritylolmesartan Medoxomil
An intermediate in the synthesis of olmesartan medoxomil
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GC49385
Halometasone
A synthetic corticosteroid
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GC49342
Glucagon-d9 (trifluoroacetate salt)
An internal standard for the quantification of glucagon
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GC49329
Turkesterone (hydrate)
A phytoecdysteroid with diverse biological activities
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GC49326
5β-Dihydroprogesterone
A progesterone receptor agonist and metabolite of progesterone
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GC49321
AZ-GHS-22
An inverse agonist of GHS-R1a
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GC49306
Isopimaric Acid
A diterpenoid resin acid
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GC49303
Ganoderic Acid DM
A triterpenoid with diverse biological activities
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GC49254
Estrone-3-Glucuronide (sodium salt hydrate)
A metabolite of 17β-estradiol