Endocrinology and Hormones

Endocrinology and Hormones
The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more
Targets for Endocrinology and Hormones
- 5-alpha Reductase(8)
- Smoothened Receptors(3)
- Androgen Receptor(117)
- Aromatase(12)
- CRTH2(2)
- Estrogen/progestogen Receptor(132)
- GnRH(21)
- Opioid Receptor(161)
- RAAS(7)
- Thyroid hormone Receptor(50)
- TRH(1)
- ROR/RAR/RXR(82)
- FXR & LXR(60)
- Glucocorticoids & Mineralocorticoids(44)
Products for Endocrinology and Hormones
- Cat.No. Product Name Information
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GC11282
β-Estradiol
Sex hormone
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GC60391
β-Casomorphin, bovine TFA
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GC61484
β-Casomorphin, human TFA
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GC45236
β-Endorphin (rat)
β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities.
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GC38030
β-Endorphin, equine (TFA)
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GC45238
δ14-Triamcinolone acetonide
δ14-Triamcinolone acetonide is a potential impurity found in commercial preparations of triamcinolone acetonide.
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GC45239
δ4-Abiraterone
δ4-Abiraterone (D4A) is an active metabolite of the CYP17A1 inhibitor abiraterone.
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GC15975
α-Estradiol
Endogenous estrogen receptor ligand
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GC33736
β-Casomorphin, bovine (β-Casomorphin-7 (bovine))
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GC33784
β-Casomorphin, human (Human β-casomorphin 7)
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GC31117
β-Endorphin, human
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GC45713
(±)-α-Tocopherol Acetate
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GC41671
(±)-Equol 4'-sulfate (sodium salt)
(±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.
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GC50708
(±)-ML 209
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GC64007
(±)-U-50488 hydrate hydrochloride
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GC15885
(±)-U-50488 hydrochloride
κ-opioid receptor agonist, selective
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GC34960
(+)-Talarozole
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GC12688
(+)-U-50488 hydrochloride
Selective κ-opioid agonist
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GC31386
(-)-PX20606 trans isomer ((-)-PX-102 trans isomer)
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GC15944
(-)-U-50488 hydrochloride
κ-opioid receptor agonist, selective
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GC34965
(20S)-Protopanaxatriol
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GA20156
(D-Ser(tBu)⁶,Azagly¹⁰)-LHRH (free base)
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GA20164
(D-Trp¹²,Tyr³⁴)-pTH (7-34) amide (bovine)
The D-Trp¹² substitution leads to a competitive pTH antagonist with increased inhibitory properties in vitro.
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GC15373
(E)-2-Decenoic acid
Fatty acid identified in royal jelly
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GC40833
(E/Z)-Endoxifen
(E/Z)-Endoxifen is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6.
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GC61491
(R)-Bicalutamide
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GC13373
(R)-DPN
estrogen receptor (ER) β agonist
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GC30710
(R)-UT-155
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GC18003
(R,R)-THC
ERα receptor agonist
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GC63292
(rac)-PF-998425
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GC49520
(S)-Equol
An estrogen receptor β agonist
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GC16372
(Z)-4-Hydroxytamoxifen
ER modulator, potent and selective
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GC62761
1α-Hydroxy-3-epi-vitamin D3
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GC41950
16α-hydroxy Estrone
The naturally-occurring estrogens are estrone, estradiol, and estriol.
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GC40454
16(S)-HETE
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
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GC17557
17 alpha-propionate
Androgen antagonist
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GC41321
17α,20β-Dihydroxy-4-pregnen-3-one
An endogenous, maturation-inducing steroid
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GC41300
17β-hydroxy Exemestane
17β-hydroxy Exemestane is the primary active metabolite of exemestane.
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GC17475
17-Hydroxyprogesterone
An endogenous progestogen and chemical intermediate
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GC18635
18-hydroxy-11-deoxy Corticosterone
18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland.
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GC35069
2,2,5,7,8-Pentamethyl-6-Chromanol
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GC49671
2,3-Oxidosqualene
An intermediate in the biosynthesis of sterols
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GC49609
2-bromo 17β-Estradiol
A synthetic steroid and inhibitor of estrogen 2-hydroxylase
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GC17160
2-hydroxy Flutamide
androgen receptor inhibitor
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GC40960
20α-dihydro Prednisolone
20α-dihydro Prednisolone is a metabolite of prednisolone.
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GC49611
21-Deoxycortisol-d8
An internal standard for the quantification of 21-deoxycortisol
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GC40968
21-hydroxy Eplerenone
21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone.
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GC14972
22(R)-hydroxy Cholesterol
endogenous agonist for LXRs
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GC18270
22(S)-hydroxy Cholesterol
A synthetic oxysterol and LXR modulator
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GC17827
24(R)-hydroxy Cholesterol
LXRα and LXRβ nuclear receptors activator
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GC40571
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.
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GC18076
24(S)-hydroxy Cholesterol
LXRα and LXRβ nuclear receptors activator
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GC33673
24-Hydroxycholesterol
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GC13431
24α-methyl Cholesterol
agonist at liver X receptors (LXR)
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GC13887
25(R)-27-hydroxy Cholesterol
LXRα and LXRβ activator
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GC11700
25(S)-27-hydroxy Cholesterol
liver x receptors (LXRα and LXRβ) activator
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GC10384
3,3',5'-Triiodo-L-thyronine
TRΔα1 activator
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GC12791
3,3'-Diindolylmethane
Anticancer and antineoplastic agent
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GC18205
3,5-Diiodothyroacetic Acid
3,5-Diiodothyroacetic acid (diac) is the acetic acid variant of thyroxine.
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GC18696
3,5-Diiodothyropropionic Acid
3,5-Diiodothyropropionic acid (DITPA) is an inotropic thyroid hormone analogue of L-thyroxine that binds to the thyroid hormone receptors TRα and TRβ (Kas = 2.4 and 4.06 x 107 M-1, respectively, for human recombinant receptors).
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GC18462
3-Formylsalicylic Acid
3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150 nM; Ki = 120 nM), the enzyme that converts estrone sulfate to estrone.
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GC42294
3-Iodothyronamine (hydrochloride)
3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine.
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GC17803
4-Hydroxytamoxifen
Estrogen receptor modulator
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GC49562
4-methoxy Estrone
An active metabolite of estrone
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GC11606
4-Methylbenzylidene camphor
ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities.
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GC42473
4-tert-Octylphenol diethoxylate
4-tert-Octylphenol diethoxylate is a degradation product of the multi-purpose surfactant, Triton X.
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GC13917
4’-hydroxy Tamoxifen
metabolite of tamoxifen, an estrogen receptor modulator
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GC40053
5α,6α-epoxy Cholestanol
An oxysterol and a metabolite of cholesterol produced by oxidation
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GC42569
5α-Androst-16-en-3-one
5α-Androst-16-en-3-one is a mammalian pheromone released as a volatile chemical cue in boar saliva to facilitate social and sexual interactions.
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GC49542
5α-Androstan-3β-ol
A steroidal androgen
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GC49326
5β-Dihydroprogesterone
A progesterone receptor agonist and metabolite of progesterone
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GC46075
5,6-dimethyl-2-Thiouracil
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GC15774
5α-dihydro-11-keto Testosterone
androgen receptor agonist
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GC49676
6β-hydroxy Budesonide
A metabolite of budesonide
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GC45969
6β-hydroxy Eplerenone
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GC49629
6β-hydroxy Prednisolone
A metabolite of prednisolone
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GC18632
6-hydroxy Bexarotene
6-hydroxy Bexarotene is an oxidative metabolite of bexarotene , a high-affinity ligand for retinoid X receptors (RXRs).
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GC18335
6β-hydroxy Dexamethasone
6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound.
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GC63764
7-α-Methylthio Spironolactone-D3
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GC17119
8-Prenylnaringenin
estrogen receptor inhibitor
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GC40464
9(R)-HETE
9(R)-HETE is an enantiomer which makes up 50% of (±)9-HETE.
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GC40465
9(S)-HETE
9(S)-HETE is an enantiomer which makes up 50% of (±)9-HETE.
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GC14596
9-cis-Retinoic Acid
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GP10060
a-MSH, amide
Melanocyte-stimulating hormones
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GC38581
Abaloparatide TFA
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GC45778
Abarelix (acetate)
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GC32843
Abarelix (R3827)
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GC35217
Abarelix Acetate
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GC50091
AC 186
Potent and selective ERβ agonist; neuroprotective
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GC11852
AC 261066
Potent RARβ2 agonist
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GC10871
AC 55649
RARβ2 agonist, potent and selective
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GP10059
Acetyl Angiotensinogen (1-14), porcine
Angiotensinogen precursor
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GC17059
Acetyl Podocarpic Acid Anhydride
LXR agonist
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GC64147
Acetyl tetrapeptide-15
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GC17094
Acitretin
Metabolite of etretinate
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GC17113
Acitretin sodium
Second-generation, systemic retinoid
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GC31738
ACP-105
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GC31530
ACTH 4-11 (Adrenocorticotropic Hormone (4-11), human)
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GC10610
Adapalene
RARβ and RARγ agonist
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GC14379
Adapalene sodium salt
Retinoic acid receptor agonist