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Home >> Signaling Pathways >> Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Targets for  Endocrinology and Hormones

Products for  Endocrinology and Hormones

  1. Cat.No. Product Name Information
  2. GC11282 β-Estradiol

    Sex hormone

     β-Estradiol Chemical Structure
  3. GC49838 α-Cortolone A metabolite of cortisol α-Cortolone Chemical Structure
  4. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  5. GC60391 β-Casomorphin, bovine TFA β-Casomorphin, bovine TFA Chemical Structure
  6. GC61484 β-Casomorphin, human TFA β-Casomorphin, human TFA Chemical Structure
  7. GC45236 β-Endorphin (rat) β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities. β-Endorphin (rat) Chemical Structure
  8. GC52494 β-Endorphin (rat) (trifluoroacetate salt) An opioid neuropeptide β-Endorphin (rat) (trifluoroacetate salt) Chemical Structure
  9. GC38005 β-Endorphin, equine β-Endorphin, equine is an endogenous opioid peptide, which binds at high affinity to both μ/δ opioid receptors. β-Endorphin, equine Chemical Structure
  10. GC38030 β-Endorphin, equine (TFA) β-Endorphin, equine (TFA) Chemical Structure
  11. GC45238 δ14-Triamcinolone acetonide δ14-Triamcinolone acetonide is a potential impurity found in commercial preparations of triamcinolone acetonide. δ14-Triamcinolone acetonide Chemical Structure
  12. GC45239 δ4-Abiraterone δ4-Abiraterone is a major metabolite of abiraterone. δ4-Abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor. δ4-Abiraterone Chemical Structure
  13. GC15975 α-Estradiol α-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia. α-Estradiol Chemical Structure
  14. GC33736 β-Casomorphin, bovine (β-Casomorphin-7 (bovine)) β-Casomorphin, bovine (β-Casomorphin-7 (bovine)) (β-Casomorphin-7 (bovine) ) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay. β-Casomorphin, bovine (β-Casomorphin-7 (bovine)) Chemical Structure
  15. GC33784 β-Casomorphin, human (Human β-casomorphin 7) is an opioid peptide, acts as an agonist of opioid receptor. β-Casomorphin, human (Human β-casomorphin 7) Chemical Structure
  16. GC31117 β-Endorphin, human β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus, is an agonist of opioid receptor, with preferred affinity for μ-opioid receptor and δ-opioid receptor; β-Endorphin, human exhibits antinociception activity. β-Endorphin, human Chemical Structure
  17. GC15938 β-Funaltrexamine hydrochloride

    μ opioid receptor antagonist

     β-Funaltrexamine hydrochloride Chemical Structure
  18. GC45713 (±)-α-Tocopherol Acetate (±)-α-Tocopherol Acetate ((±)-Vitamin E acetate), is a orally active synthetic form of vitamin E. (±)-α-Tocopherol Acetate Chemical Structure
  19. GC41671 (±)-Equol 4'-sulfate (sodium salt)

    (±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.

     (±)-Equol 4'-sulfate (sodium salt) Chemical Structure
  20. GC50708 (±)-ML 209 An RORγt antagonist (±)-ML 209 Chemical Structure
  21. GC64007 (±)-U-50488 hydrate hydrochloride (±)-U-50488 hydrate hydrochloride Chemical Structure
  22. GC15885 (±)-U-50488 hydrochloride

    κ-opioid receptor agonist, selective

     (±)-U-50488 hydrochloride Chemical Structure
  23. GC34960 (+)-Talarozole (+)-Talarozole is a potent inhibitor of retinoic acid metabolism extracted from patent WO 1997049704 A1. (+)-Talarozole Chemical Structure
  24. GC12688 (+)-U-50488 hydrochloride Selective κ-opioid agonist (+)-U-50488 hydrochloride Chemical Structure
  25. GC31386 (-)-PX20606 trans isomer ((-)-PX-102 trans isomer) (-)-PX20606 trans isomer ((-)-PX-102 trans isomer) is a FXR agonist with EC50s of 18 and 29 nM for FXR in FRET and M1H assay, respectively. (-)-PX20606 trans isomer ((-)-PX-102 trans isomer) Chemical Structure
  26. GC15944 (-)-U-50488 hydrochloride κ-opioid receptor agonist, selective (-)-U-50488 hydrochloride Chemical Structure
  27. GC70081 (1R,2R)-U-50488 hydrochloride

    (1R,2R)-U-50488 hydrochloride is the absolute configuration of (±)-U-50488 hydrochloride. (±)-U-50488 hydrochloride is a κ opioid receptor agonist.

     (1R,2R)-U-50488 hydrochloride Chemical Structure
  28. GC34965 (20S)-Protopanaxatriol An active ginsenoside metabolite (20S)-Protopanaxatriol Chemical Structure
  29. GA20156 (D-Ser(tBu)⁶,Azagly¹⁰)-LHRH (free base) (D-Ser(tBu)⁶,Azagly¹⁰)-LHRH (free base) Chemical Structure
  30. GA20164 (D-Trp¹²,Tyr³⁴)-pTH (7-34) amide (bovine) (D-Trp¹²,Tyr³⁴)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp¹²,Tyr³⁴)-pTH (7-34) amide (bovine) Chemical Structure
  31. GC15373 (E)-2-Decenoic acid An unsaturated fatty acid found in royal jelly (E)-2-Decenoic acid Chemical Structure
  32. GC46336 (E)-Guggulsterone A farnesoid X receptor antagonist (E)-Guggulsterone Chemical Structure
  33. GC49189 (E/Z)-4-hydroxy Tamoxifen-d5 An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen (E/Z)-4-hydroxy Tamoxifen-d5 Chemical Structure
  34. GC40833 (E/Z)-Endoxifen (E/Z)-Endoxifen is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. (E/Z)-Endoxifen Chemical Structure
  35. GC61491 (R)-Bicalutamide (R)-Bicalutamide is the (R)-enantiomer of Bicalutamide. (R)-Bicalutamide is an androgen receptor (AR) antagonist, with antineoplastic activity. (R)-Bicalutamide is widely used for the research of prostate cancer. (R)-Bicalutamide Chemical Structure
  36. GC13373 (R)-DPN estrogen receptor (ER) β agonist (R)-DPN Chemical Structure
  37. GC30710 (R)-UT-155 (R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. Less active than the S-isomer. (R)-UT-155 Chemical Structure
  38. GC18003 (R,R)-THC ERα receptor agonist (R,R)-THC Chemical Structure
  39. GC52185 (R,S)-Anatabine-d4 (R,S)-Anatabine-d4 Chemical Structure
  40. GC63292 (rac)-PF-998425 (Rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 Chemical Structure
  41. GC69798 (Rac)-SNC80

    (Rac)-SNC80 is the racemic form of SNC80. SNC80 (NIH 10815) is an effective and highly selective non-peptide delta-opioid receptor agonist with a Ki of 1.78 nM and IC50 of 2.73 nM. SNC80 has anti-nociceptive, anti-hyperalgesic, and antidepressant-like effects, and can be used in research on various types of headaches.

     (Rac)-SNC80 Chemical Structure
  42. GC49520 (S)-Equol An estrogen receptor β agonist (S)-Equol Chemical Structure
  43. GC16372 (Z)-4-Hydroxytamoxifen (Z)-4-Hydroxytamoxifen is a metabolite of Tamoxifen. (Z)-4-Hydroxytamoxifen shows higher affinity for the ER than Tamoxifen. (Z)-4-Hydroxytamoxifen induces a non-apoptotic cytotoxic effect in human endometrial adenocarcinoma cells. (Z)-4-Hydroxytamoxifen Chemical Structure
  44. GC62761 1α-Hydroxy-3-epi-vitamin D3 1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion. 1α-Hydroxy-3-epi-vitamin D3 Chemical Structure
  45. GC48787 11β-Hydroxyetiocholanolone A metabolite of hydrocortisone 11β-Hydroxyetiocholanolone Chemical Structure
  46. GC48710 11-Dehydrocorticosterone An endogenous mineralocorticoid 11-Dehydrocorticosterone Chemical Structure
  47. GC49161 16α-hydroxy Dehydroepiandrosterone A metabolite of dehydroepiandrosterone 16α-hydroxy Dehydroepiandrosterone Chemical Structure
  48. GC41950 16α-hydroxy Estrone The naturally-occurring estrogens are estrone, estradiol, and estriol. 16α-hydroxy Estrone Chemical Structure
  49. GC46456 16α-Hydroxyetiocholanolone A metabolite of 16α-DHEA and androstenedione 16α-Hydroxyetiocholanolone Chemical Structure
  50. GC40454 16(S)-HETE Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16(S)-HETE Chemical Structure
  51. GC49068 16-Epiestriol A metabolite of estrone 16-Epiestriol Chemical Structure
  52. GC49848 16-Ketoestradiol An active metabolite of estrone 16-Ketoestradiol Chemical Structure
  53. GC17557 17 alpha-propionate A peripherally selective androgen receptor antagonist 17 alpha-propionate Chemical Structure
  54. GC41321 17α,20β-Dihydroxy-4-pregnen-3-one An endogenous, maturation-inducing steroid 17α,20β-Dihydroxy-4-pregnen-3-one Chemical Structure
  55. GC46470 17β-Estradiol-d2 17β-Estradiol-d2 (β-17β-Estradiol-d2) is the deuterium labeled Estradiol. 17β-Estradiol-d2 Chemical Structure
  56. GC41300 17β-hydroxy Exemestane 17β-hydroxy Exemestane is the primary active metabolite of exemestane. 17β-hydroxy Exemestane Chemical Structure
  57. GC48819 17-Epiestriol A metabolite of estrone 17-Epiestriol Chemical Structure
  58. GC17475 17-Hydroxyprogesterone An endogenous progestogen and chemical intermediate 17-Hydroxyprogesterone Chemical Structure
  59. GC18635 18-hydroxy-11-deoxy Corticosterone 18-hydroxy-11-deoxy Corticosterone (18-OH-DOC) is a mineralocorticoid secreted by the zona fasciculata of the adrenal gland. 18-hydroxy-11-deoxy Corticosterone Chemical Structure
  60. GC35069 2,2,5,7,8-Pentamethyl-6-Chromanol 2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines. 2,2,5,7,8-Pentamethyl-6-Chromanol Chemical Structure
  61. GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene Chemical Structure
  62. GC66679 2,6-Dimethyl-L-tyrosine 2,6-Dimethyl-L-tyrosine (Dmt) is a tyrosine derivative that enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides. 2,6-Dimethyl-L-tyrosine Chemical Structure
  63. GC49609 2-bromo 17β-Estradiol A synthetic steroid and inhibitor of estrogen 2-hydroxylase 2-bromo 17β-Estradiol Chemical Structure
  64. GC49172 2-hydroxy Estrone An active metabolite of estrone 2-hydroxy Estrone Chemical Structure
  65. GC17160 2-hydroxy Flutamide 2-hydroxy Flutamide (HF), an active metabolite of Flutamide, is a potent androgen receptor antagonist (IC50=700 nM). 2-hydroxy Flutamide can be used for the research of prostate cancer. 2-hydroxy Flutamide Chemical Structure
  66. GC48910 2-Hydroxyanthraquinone An anthraquinone with antibacterial and estrogenic activities 2-Hydroxyanthraquinone Chemical Structure
  67. GC40960 20α-dihydro Prednisolone 20α-dihydro Prednisolone is a metabolite of prednisolone. 20α-dihydro Prednisolone Chemical Structure
  68. GC46526 21-Deoxycortisol A corticosteroid metabolite of 17-hydroxyprogesterone 21-Deoxycortisol Chemical Structure
  69. GC49611 21-Deoxycortisol-d8 An internal standard for the quantification of 21-deoxycortisol 21-Deoxycortisol-d8 Chemical Structure
  70. GC52083 21-Deoxycortisone A corticosteroid metabolite of 11-keto progesterone 21-Deoxycortisone Chemical Structure
  71. GC40968 21-hydroxy Eplerenone 21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone. 21-hydroxy Eplerenone Chemical Structure
  72. GC14972 22(R)-hydroxy Cholesterol endogenous agonist for LXRs 22(R)-hydroxy Cholesterol Chemical Structure
  73. GC18270 22(S)-hydroxy Cholesterol A synthetic oxysterol and LXR modulator 22(S)-hydroxy Cholesterol Chemical Structure
  74. GC17827 24(R)-hydroxy Cholesterol

    LXRα and LXRβ nuclear receptors activator

     24(R)-hydroxy Cholesterol Chemical Structure
  75. GC40571 24(S),25-epoxy Cholesterol

    24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.

     24(S),25-epoxy Cholesterol Chemical Structure
  76. GC18076 24(S)-hydroxy Cholesterol

    LXRα and LXRβ nuclear receptors activator

     24(S)-hydroxy Cholesterol Chemical Structure
  77. GC33673 24-Hydroxycholesterol 24-Hydroxycholesterol is a natural sterol, which serves as a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR. 24-Hydroxycholesterol Chemical Structure
  78. GC13431 24α-methyl Cholesterol 24α-methyl Cholesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects. 24α-methyl Cholesterol Chemical Structure
  79. GC13887 25(R)-27-hydroxy Cholesterol 25(R)-27-hydroxy Cholesterol is a selective estrogen receptor modulator and an agonist of the liver X receptor. 25(R)-27-hydroxy Cholesterol Chemical Structure
  80. GC11700 25(S)-27-hydroxy Cholesterol liver x receptors (LXRα and LXRβ) activator 25(S)-27-hydroxy Cholesterol Chemical Structure
  81. GC10384 3,3',5'-Triiodo-L-thyronine 3,3',5'-Triiodo-L-thyronine is a thyroid hormone generated by deiodination of the prohormone thyroxine. 3,3',5'-Triiodo-L-thyronine Chemical Structure
  82. GC48395 3,3',5-Triiodo-L-thyronine (sodium salt hydrate) 3,3',5-Triiodo-L-thyronine (sodium salt hydrate) is an active form of thyroid hormone. 3,3',5-Triiodo-L-thyronine (sodium salt hydrate) Chemical Structure
  83. GC12791 3,3'-Diindolylmethane A phytochemical with antiradiation and chemopreventative effects 3,3'-Diindolylmethane Chemical Structure
  84. GC49427 3,5-Diiodo-L-thyronine 3,5-Diiodo-L-thyronine is an endogenous metabolite. 3,5-Diiodo-L-thyronine Chemical Structure
  85. GC18205 3,5-Diiodothyroacetic Acid 3,5-Diiodothyroacetic acid (diac) is the acetic acid variant of thyroxine. 3,5-Diiodothyroacetic Acid Chemical Structure
  86. GC18696 3,5-Diiodothyropropionic Acid 3,5-Diiodothyropropionic acid (DITPA) is an inotropic thyroid hormone analogue of L-thyroxine that binds to the thyroid hormone receptors TRα and TRβ (Kas = 2.4 and 4.06 x 107 M-1, respectively, for human recombinant receptors). 3,5-Diiodothyropropionic Acid Chemical Structure
  87. GC52129 3-Amino-5-hydroxybenzoic Acid 3-Amino-5-hydroxybenzoic Acid Chemical Structure
  88. GC49180 3-epi-25-hydroxy Vitamin D3 The C-3 epimer of 25-hydroxy vitamin D3 3-epi-25-hydroxy Vitamin D3 Chemical Structure
  89. GC18462 3-Formylsalicylic Acid 3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150 nM; Ki = 120 nM), the enzyme that converts estrone sulfate to estrone. 3-Formylsalicylic Acid Chemical Structure
  90. GC42294 3-Iodothyronamine (hydrochloride) 3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. 3-Iodothyronamine (hydrochloride) Chemical Structure
  91. GC48824 4-hydroxy Estrone A metabolite of estrone 4-hydroxy Estrone Chemical Structure
  92. GC17803 4-Hydroxytamoxifen 4-Hydroxytamoxifen (Afimoxifene) is a racemic compound of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen isomers. 4-Hydroxytamoxifen is an estrogen receptor modulator. 4-Hydroxytamoxifen Chemical Structure
  93. GC49562 4-methoxy Estrone An active metabolite of estrone 4-methoxy Estrone Chemical Structure
  94. GC11606 4-Methylbenzylidene camphor ultraviolet light blocker used in cosmetics and sunscreen preparations that also has estrogenic activities. 4-Methylbenzylidene camphor Chemical Structure
  95. GC42473 4-tert-Octylphenol diethoxylate 4-tert-Octylphenol diethoxylate is a degradation product of the multi-purpose surfactant, Triton X. 4-tert-Octylphenol diethoxylate Chemical Structure
  96. GC52365 4-tert-Octylphenol monoethoxylate An alkylphenolethoxylate and a degradation product of non-ionic surfactants 4-tert-Octylphenol monoethoxylate Chemical Structure
  97. GC13917 4’-hydroxy Tamoxifen metabolite of tamoxifen, an estrogen receptor modulator 4’-hydroxy Tamoxifen Chemical Structure
  98. GC40053 5α,6α-epoxy Cholestanol An oxysterol and a metabolite of cholesterol produced by oxidation 5α,6α-epoxy Cholestanol Chemical Structure
  99. GC42569 5α-Androst-16-en-3-one 5α-Androst-16-en-3-one is a mammalian pheromone released as a volatile chemical cue in boar saliva to facilitate social and sexual interactions. 5α-Androst-16-en-3-one Chemical Structure
  100. GC49542 5α-Androstan-3β-ol A steroidal androgen 5α-Androstan-3β-ol Chemical Structure
  101. GC48808 5β-Androstane-3α,17β-diol A metabolite of testosterone 5β-Androstane-3α,17β-diol Chemical Structure

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