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Home >> Signaling Pathways >> Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for  Endocrinology and Hormones

  1. Cat.No. Product Name Information
  2. GC25832 Raloxifene Raloxifene (Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. Raloxifene Chemical Structure
  3. GC25627 Menotropin Menotropin (Human Menopausal Gonadotrophin) is a hormonally active medication for the treatment of fertility disturbances, which are extracted from the urine of postmenopausal women. Menotropin Chemical Structure
  4. GC25410 Fasiglifam (TAK-875) Fasiglifam (TAK-875) is a selective GPR40 agonist with EC50 of 14 nM in human GPR40 expressing CHO cell line, 400-fold more potent than oleic acid. Fasiglifam (TAK-875) Chemical Structure
  5. GC68427 GSK1521498 free base GSK1521498 free base Chemical Structure
  6. GC68337 Parathyroid hormone (1-34) (rat) acetate Parathyroid hormone (1-34) (rat) acetate Chemical Structure
  7. GC68212 Chenodeoxycholic acid-13C Chenodeoxycholic acid-13C Chemical Structure
  8. GC67956 Endomorphin 1 acetate Endomorphin 1 acetate Chemical Structure
  9. GC67907 CCG258747 CCG258747 Chemical Structure
  10. GC67703 Adrenocorticotropic hormone TFA Adrenocorticotropic hormone TFA Chemical Structure
  11. GC67698 Androgen receptor-IN-2 Androgen receptor-IN-2 Chemical Structure
  12. GC52506 Ghrelin (human) (trifluoroacetate salt) A growth hormone releasing peptide Ghrelin (human) (trifluoroacetate salt) Chemical Structure
  13. GC52494 β-Endorphin (rat) (trifluoroacetate salt) An opioid neuropeptide β-Endorphin (rat) (trifluoroacetate salt) Chemical Structure
  14. GC52490 Glucagon (hydrochloride) A peptide hormone Glucagon (hydrochloride) Chemical Structure
  15. GC52420 Drospirenone-13C3 An internal standard for the quantification of drospirenone Drospirenone-13C3 Chemical Structure
  16. GC52415 Angiotensin A (trifluoroacetate salt) An AT1 and AT2 receptor agonist and active metabolite of angiotensin II Angiotensin A (trifluoroacetate salt) Chemical Structure
  17. GC52414 [Ala17]-MCH (trifluoroacetate salt) An MCH-derived peptide and MCH receptor agonist [Ala17]-MCH (trifluoroacetate salt) Chemical Structure
  18. GC52390 Spexin 1 (human, mouse, rat, bovine) (acetate) An endogenous peptide and agonist of GAL2 and GAL3 Spexin 1 (human, mouse, rat, bovine) (acetate) Chemical Structure
  19. GC52388 [D-Lys3]-GHRP-6 (trifluoroacetate salt) An antagonist of GHS-R1a [D-Lys3]-GHRP-6 (trifluoroacetate salt) Chemical Structure
  20. GC52387 Crosstide (trifluoroacetate salt) A peptide substrate for Akt Crosstide (trifluoroacetate salt) Chemical Structure
  21. GC52365 4-tert-Octylphenol monoethoxylate An alkylphenolethoxylate and a degradation product of non-ionic surfactants 4-tert-Octylphenol monoethoxylate Chemical Structure
  22. GC52351 Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide A biotinylated and citrullinated α-enolase peptide Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide Chemical Structure
  23. GC52329 Betamethasone-d5 An internal standard for the quantification of betamethasone Betamethasone-d5 Chemical Structure
  24. GC52325 MeTC7 A vitamin D receptor antagonist MeTC7 Chemical Structure
  25. GC52281 Losartan Azide A potential impurity in commercial preparations of losartan Losartan Azide Chemical Structure
  26. GC52242 V-125 An RXR agonist V-125 Chemical Structure
  27. GC66679 2,6-Dimethyl-L-tyrosine 2,6-Dimethyl-L-tyrosine (Dmt) is a tyrosine derivative that enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides. 2,6-Dimethyl-L-tyrosine Chemical Structure
  28. GC66433 Ro 41-5253 Ro 41-5253 is an orally active selective retinoic acid receptor alpha (RARα) antagonist. Ro 41-5253 can bind RARα without inducing transcription or affecting RAR/RXR heterodimerization and DNA binding. Ro 41-5253 can inhibit cancer cell proliferation and induce apoptosis, has antitumor activity. Ro 41-5253 Chemical Structure
  29. GC66207 Atraric acid Atraric acid (Methyl atrarate) is a specific androgen receptor (AR) antagonist with anti-inflammatory and anticancer effects. Atraric acid represses the expression of the endogenous prostate specific antigen gene in both LNCaP and C4-2 cells. Atraric acid can also inhibit the synthesis of NO and cytokine, and suppress the MAPK-NFκB signaling pathway. Atraric acid can be used to research prostate diseases and inflammatory diseases. Atraric acid Chemical Structure
  30. GC65936 Larsucosterol (trimethylamine) Larsucosterol (DUR-928) trimethylamine, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol trimethylamine as a potent endogenous regulator decreases lipogenesis. Larsucosterol trimethylamine inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of SREBP-1. Larsucosterol (trimethylamine) Chemical Structure
  31. GC52189 Nomegestrol Nomegestrol is a potent and orally available progestin, acts as a selective full progesterone receptor agonist, with a Kd of 5.44 nM for rat uterine progesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity. Nomegestrol Chemical Structure
  32. GC52185 (R,S)-Anatabine-d4 (R,S)-Anatabine-d4 Chemical Structure
  33. GC52180 WAY-169916 WAY-169916 is a pathway-selective ligand of ER (estrogen receptor) that acts by inhibiting NF-kB transcriptional activity. WAY-169916 Chemical Structure
  34. GC52129 3-Amino-5-hydroxybenzoic Acid 3-Amino-5-hydroxybenzoic Acid Chemical Structure
  35. GC65587 CO23 CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation. CO23 Chemical Structure
  36. GC65260 EDP-305 EDP-305 is an orally active, potent and selective farnesoid X receptor (FXR) agonist, with EC50 values of 34 nM (chimeric FXR in CHO cells) and 8 nM (full-length FXR in HEK cells). EDP-305 Chemical Structure
  37. GC65255 Trestolone Trestolone Chemical Structure
  38. GC64854 Enzalutamide-d3 Enzalutamide D3 is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. Enzalutamide-d3 Chemical Structure
  39. GC64600 SK33 SK33, a trifluoromethylated enobosarm analog, is a potent, and tissue selective anti-androgen. SK33reduces androgen receptor (AR) transcriptional activity. SK33 Chemical Structure
  40. GC64586 Nandrolone laurate Nandrolone laurate Chemical Structure
  41. GC64540 Ar-V7-IN-1 Ar-V7-IN-1 is a potent inhibitor of Ar-V7. AR-V7 is a hormone-independent splice variant of the androgen receptor. Ar-V7-IN-1 has the potential for the research of various indications, in particular cancers such as prostate cancer (extracted from patent WO2018114781A1, compound 43). Ar-V7-IN-1 Chemical Structure
  42. GC52083 21-Deoxycortisone A corticosteroid metabolite of 11-keto progesterone 21-Deoxycortisone Chemical Structure
  43. GC52043 Hydrocortisone Aceponate Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid. Hydrocortisone Aceponate Chemical Structure
  44. GC52021 L-Thyroxine-N-methylamide A potential impurity found in commercial preparations of L-thyroxine L-Thyroxine-N-methylamide Chemical Structure
  45. GC64301 DS08210767 DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM. DS08210767 Chemical Structure
  46. GC64147 Acetyl tetrapeptide-15 Acetyl tetrapeptide-15 is a synthetic peptide used in the cosmetics for sensitive skin. Acetyl tetrapeptide-15 Chemical Structure
  47. GC64007 (±)-U-50488 hydrate hydrochloride (±)-U-50488 hydrate hydrochloride Chemical Structure
  48. GC63935 Testosterone buciclate Testosterone buciclate Chemical Structure
  49. GC63932 Amsilarotene Amsilarotene (TAC-101; Am 555S), an orally active synthetic retinoid, has selective affinity for retinoic acid receptor α (RAR-α) binding with Ki of 2.4, 400 nM for RAR-α and RAR-β. Amsilarotene induces the apoptotic of human gastric cancer, hepatocellular carcinoma and ovarian carcinoma cells. Amsilarotene can be used for the research of cancer. Amsilarotene Chemical Structure
  50. GC63884 Linzagolix Linzagolix (KLH-2109; OBE-2109) is a potent, non-peptide, and orally active GnRH antagonist. Linzagolix Chemical Structure
  51. GC49680 Clobetasone Propionate A corticosteroid Clobetasone Propionate Chemical Structure
  52. GC49679 Sauvagine (trifluoroacetate salt) A neuropeptide hormone Sauvagine (trifluoroacetate salt) Chemical Structure
  53. GC49676 6β-hydroxy Budesonide A metabolite of budesonide 6β-hydroxy Budesonide Chemical Structure
  54. GC49671 2,3-Oxidosqualene An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene Chemical Structure
  55. GC49654 BMS 270394 A RARγ agonist BMS 270394 Chemical Structure
  56. GC49653 Ramipril Diketopiperazine A potential impurity found in commercial preparations of ramipril Ramipril Diketopiperazine Chemical Structure
  57. GC49648 Enobosarm-d4 An internal standard for the quantification of enobosarm Enobosarm-d4 Chemical Structure
  58. GC49634 Isoflupredone Isoflupredone belongs to the class of corticosteroids and exerts its effect by binding to glucocorticoid and mineralocorticoid receptors of animals, such as horses. Isoflupredone Chemical Structure
  59. GC49631 Fluocortolone A glucocorticoid Fluocortolone Chemical Structure
  60. GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone 6β-hydroxy Prednisolone Chemical Structure
  61. GC49611 21-Deoxycortisol-d8 An internal standard for the quantification of 21-deoxycortisol 21-Deoxycortisol-d8 Chemical Structure
  62. GC49609 2-bromo 17β-Estradiol A synthetic steroid and inhibitor of estrogen 2-hydroxylase 2-bromo 17β-Estradiol Chemical Structure
  63. GC49592 Sermorelin (acetate) A growth hormone-releasing hormone analog Sermorelin (acetate) Chemical Structure
  64. GC49574 Somatostatin-28 (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) A cyclic neuropeptide hormone Somatostatin-28 (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  65. GC49563 Fenhexamid Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid Chemical Structure
  66. GC49562 4-methoxy Estrone An active metabolite of estrone 4-methoxy Estrone Chemical Structure
  67. GC49542 5α-Androstan-3β-ol A steroidal androgen 5α-Androstan-3β-ol Chemical Structure
  68. GC49520 (S)-Equol An estrogen receptor β agonist (S)-Equol Chemical Structure
  69. GC49475 Triptorelin (trifluoroacetate salt) A synthetic GNRH peptide agonist Triptorelin (trifluoroacetate salt) Chemical Structure
  70. GC49459 Desmopressin (trifluoroacetate salt) A vasopressin receptor agonist Desmopressin (trifluoroacetate salt) Chemical Structure
  71. GC63764 7-α-Methylthio Spironolactone-D3 7-α-Methylthio Spironolactone-D3 Chemical Structure
  72. GC63755 Exemestane-D2 Exemestane-D2 Chemical Structure
  73. GC63686 Naloxone methiodide Naloxone methiodide Chemical Structure
  74. GC63595 NH-3 NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. NH-3 Chemical Structure
  75. GC63579 Linuron Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron Chemical Structure
  76. GC63431 DPDPE TFA DPDPE TFA, an opioid peptide, is a selective δ-opioid receptor?(DOR) agonist?with anticonvulsant effects. DPDPE TFA Chemical Structure
  77. GC63402 Rezvilutamide Rezvilutamide (SHR3680) is an androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer. Rezvilutamide Chemical Structure
  78. GC63292 (rac)-PF-998425 (Rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 Chemical Structure
  79. GC63217 Testosterone undecanoate Testosterone undecanoate Chemical Structure
  80. GC63200 Spiradoline Spiradoline Chemical Structure
  81. GC63115 Nociceptin (1-13), amide TFA Nociceptin (1-13), amide TFA is a potent ORL1 receptor (opioid receptor-like 1 receptor, OP4) agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes. Nociceptin (1-13), amide TFA Chemical Structure
  82. GC63096 Nandrolone phenylpropionate Nandrolone phenylpropionate Chemical Structure
  83. GC63072 Methyl-6-alpha-Naltrexol Methyl-6-alpha-Naltrexol Chemical Structure
  84. GC63066 Methenolone acetate Methenolone acetate Chemical Structure
  85. GC62992 Glutaurine Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine Chemical Structure
  86. GC62761 1α-Hydroxy-3-epi-vitamin D3 1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion. 1α-Hydroxy-3-epi-vitamin D3 Chemical Structure
  87. GC49427 3,5-Diiodo-L-thyronine 3,5-Diiodo-L-thyronine is an endogenous metabolite. 3,5-Diiodo-L-thyronine Chemical Structure
  88. GC49423 Metanephrine-d3 (hydrochloride) An internal standard for the quantification of metanephrine Metanephrine-d3 (hydrochloride) Chemical Structure
  89. GC49408 Ramipril Diketopiperazine Acid A potential impurity found in commercial preparations of ramipril Ramipril Diketopiperazine Acid Chemical Structure
  90. GC49399 N-Desbutyl Dronedarone (hydrochloride) Debutyldronedarone (SR35021) hydrochloride, the main metabolite of Dronedarone, is a selective thyroid hormone receptor α1 (TRα1) inhibitor. N-Desbutyl Dronedarone (hydrochloride) Chemical Structure
  91. GC49393 all-trans-13,14-Dihydroretinol A metabolite of all-trans retinoic acid all-trans-13,14-Dihydroretinol Chemical Structure
  92. GC49391 7α-Thiospironolactone An active metabolite of spironolactone 7α-Thiospironolactone Chemical Structure
  93. GC49389 Tritylolmesartan Medoxomil An intermediate in the synthesis of olmesartan medoxomil Tritylolmesartan Medoxomil Chemical Structure
  94. GC49385 Halometasone A synthetic corticosteroid Halometasone Chemical Structure
  95. GC49342 Glucagon-d9 (trifluoroacetate salt) An internal standard for the quantification of glucagon Glucagon-d9 (trifluoroacetate salt) Chemical Structure
  96. GC49329 Turkesterone (hydrate) A phytoecdysteroid with diverse biological activities Turkesterone (hydrate) Chemical Structure
  97. GC49326 5β-Dihydroprogesterone A progesterone receptor agonist and metabolite of progesterone 5β-Dihydroprogesterone Chemical Structure
  98. GC49321 AZ-GHS-22 An inverse agonist of GHS-R1a AZ-GHS-22 Chemical Structure
  99. GC49306 Isopimaric Acid A diterpenoid resin acid Isopimaric Acid Chemical Structure
  100. GC49303 Ganoderic Acid DM A triterpenoid with diverse biological activities Ganoderic Acid DM Chemical Structure
  101. GC49254 Estrone-3-Glucuronide (sodium salt hydrate) A metabolite of 17β-estradiol Estrone-3-Glucuronide (sodium salt hydrate) Chemical Structure

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