GLPBio

α-Helical CRF(9-41) TFA

Catalog No.: GC84823Purity:>99.50%
COASDSData Sheet
α-Helical CRF(9-41) TFA is a competitive CRF2 receptor antagonist with K B of ~100 nM.

Products are for research use only. Not for human use. We do not sell to patients.

α-Helical CRF(9-41) TFA
1mgIn Stock
$99.00
1
5mgIn Stock
$234.00
1
10mgIn Stock
$369.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

α-Helical CRF(9-41) TFA is a competitive CRF2 receptor antagonist with K B of ~100 nM. α-Helical CRF(9-41) TFA is also a partial agonist of CRF1 receptor with an EC 50 of 140 nM [1] [2].

References:
[1]. Sonia Tucci, et al. Corticotropin releasing factor antagonist, alpha-helical CRF(9-41), reverses nicotine-induced conditioned, but not unconditioned, anxiety. Psychopharmacology (Berl). 2003 May;167(3):251-6.
[2]. Smart D, et al. Characterisation using microphysiometry of CRF receptor pharmacology. Eur J Pharmacol. 1999 Aug 27;379(2-3):229-35.

Product Documents

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

Molecular Formula
C168H275F3N46O55S2
Molecular Weight
3940.42
Solubility
H2O: 1.82 mg/mL (0.46 mM; ultrasonic and adjust pH to 3 with HCl)
Storage
Sealed storage, away from moisture
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

Review for α-Helical CRF(9-41) TFA

Rating: 5
  • 5 Star100%
  • 4 Star0%
  • 3 Star0%
  • 2 Star0%
  • 1 Star0%