Abietic Acid
Catalog No.: GC40831Purity:>98.00%Synonyms: (-)-Abietic Acid, NSC 25149, Sylvic Acid
Abietic acid is an abietane diterpene originally isolated from wood resin that has diverse biological activities, including enzyme inhibitory, antiproliferative, antibacterial, and anti-obesity properties.
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Cas No.: 514-10-3
10mM (in 1mL DMSO)In Stock
$45.00
1
5mgIn Stock
$45.00
1
10mgIn Stock
$70.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $45.00 | In Stock | 1 | |
| 5mg | $45.00 | In Stock | 1 | |
| 10mg | $70.00 | In Stock | 1 |
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Citations
1 publicationsPublications from researchers using this productDescription
Abietic acid is an abietane diterpene originally isolated from wood resin that has diverse biological activities, including enzyme inhibitory, antiproliferative, antibacterial, and anti-obesity properties. It inhibits soybean 5-lipoxygenase (5-LO) and rat prostate testosterone 5α-reductase in cell-free assays (IC50s = 29.5 and 56 μM, respectively). Abietic acid selectively inhibits proliferation of HeLa cervical cancer cells over noncancerous Vero cells (IC50s = 15 and 53 μM, respectively) and inhibits the growth of S. epidermidis, P. acnes, and S. mitis bacteria (MICs = 8, 4, and 16 μg/ml, respectively). It induces expression of fatty acid binding protein 2 and lipoprotein lipase (LPL) in differentiated 3T3-L1 mouse adipocytes when used at a concentration of 25 μM. Abietic acid (40 mg/kg per day) also decreases body and adipose tissue weight in mice fed a high-fat diet.
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
514-10-3
Synonyms
(-)-Abietic Acid, NSC 25149, Sylvic Acid
SMILES
CC(C)C1=CC2=CC[C@@]3([H])[C@](C)(C(O)=O)CCC[C@]3(C)[C@@]2([H])CC1
Molecular Formula
C20H30O2
Molecular Weight
302.5
Solubility
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:20): 0.04 mg/ml,Ethanol: 20 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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