Adenosine-3',5'-bisphosphate ammonium is a XRN1 inhibitor ( IC50 = 36 nM). Adenosine-3',5'-bisphosphate ammonium can be used in the study of colorectal cancer, breast cancer and lung cancer [1].
References:
[1]. Lockbaum GJ, et al. Characterization of exoribonuclease XRN1 as a cancer target and identification of adenosine-3',5'-bisphosphate as a potent enzyme inhibitor. Commun Biol. 2025 Apr 9;8(1):589.
References:
[1]. Lockbaum GJ, et al. Characterization of exoribonuclease XRN1 as a cancer target and identification of adenosine-3',5'-bisphosphate as a potent enzyme inhibitor. Commun Biol. 2025 Apr 9;8(1):589.
















