GLPBio

AM-4668

Catalog No.: GC34464Purity:>99.00%
COASDSData Sheet
AM-4668 is a GPR40 agonist for type 2 diabetes.

Products are for research use only. Not for human use. We do not sell to patients.

AM-4668
Cas No.: 1011531-27-3
5mgQuote
$252.00
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively[1]. EC50: 3.6 nM (GPR40, in A9 cells), 36 nM (GPR40, in CHO cells)[1]

[1]. Liu JJ, et al. Optimization of GPR40 Agonists for Type 2 Diabetes. ACS Med Chem Lett. 2014 Feb 6;5(5):517-21.

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1011531-27-3
SMILES
OC(C[C@H](C1=NOC=C1)C(C=C2)=CC=C2OCC(S3)=C(C)N=C3C4=CC=C(C(F)(F)F)C=C4)=O
Molecular Formula
C24H19F3N2O4S
Molecular Weight
488.48
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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