GLPBio

Amg-1

Catalog No.: GC79679Purity:>98.00%
COASDSData Sheet
Amg-1 is a potent, reversible and selective indoleamine 2,3-dioxygenase ( IDO1 ) inhibitor ( IC50 = 3.0 μM).

Products are for research use only. Not for human use. We do not sell to patients.

Amg-1
Cas No.: 496023-55-3
1mgIn Stock
$104.00
1
5mgIn Stock
$264.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    Nature
    641, 529–536 (2025)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Amg-1 is a potent, reversible and selective indoleamine 2,3-dioxygenase ( IDO1 ) inhibitor ( IC50 = 3.0 μM). Amg-1 exhibits >80-fold selectivity over IDO2 ( IC50 > 250 μM) and >20-fold selective over TDO ( IC50 > 62.5 μM). Amg-1 can be used for cancer, hypotension, and neurological disorders research [1].

References:
[1]. Meininger D, et al. Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors. Biochim Biophys Acta. 2011 Dec;1814(12):1947-54.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
496023-55-3
Molecular Formula
C20H16N4O3S2
Molecular Weight
424.5
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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