GLPBio

Anatibant hydrochloride

Catalog No.: GC72919Synonyms: LF 16-0687 hydrochloride; XY-2405 hydrochloride
COASDSData Sheet
Anatibant (LF 16-0687; XY-2405) drochloride is a selective non-peptide bradykinin B2 receptor antagonist.

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Anatibant hydrochloride
Cas No.: 209788-45-4
1 mgIn Stock
$332.00
1
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Description

Anatibant (LF 16-0687; XY-2405) drochloride is a selective non-peptide bradykinin B2 receptor antagonist. Anatibant drochloride binds to the human, rat and guinea-pig recombinant B2 receptor with Ki values of 0.67 nM, 1.74 nM and 1.37 nM, respectively. Anatibant drochloride crosses the blood-brain barrier (BBB). Anatibant drochloride can be used in research on brain damage diseases.

References:
[1]. Klaus Zweckberger, et al. Anatibant, a selective non-peptide bradykinin B2 receptor antagonist, reduces intracranial pertension and histopathological damage after experimental traumatic brain injury. Neurosci Lett. 2009 Apr 24;454(2):115-7.
[2]. D Pruneau, et al. Pharmacological profile of LF 16-0687, a new potent non-peptide bradykinin B2 receptor antagonist. Immunopharmacology. 1999 Sep;43(2-3):187-94.

Product Documents

Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
209788-45-4
Synonyms
LF 16-0687 hydrochloride; XY-2405 hydrochloride
Molecular Formula
C34H38Cl4N6O5S
Molecular Weight
784.58
Solubility
DMSO : 55 mg/mL (70.10 mM; Need ultrasonic and warming)
Storage
-20°C, sealed storage, away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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