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Anti-Inflammatory Peptide 1

Catalog No.GP10124

Anti-Inflammatory Peptide 1 Chemical Structure

PLA2 inhibitor

Size Price Stock Qty
5mg
$45.00
In stock
10mg
$74.00
In stock
25mg
$93.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Anti-Inflammatory Peptide 1 (C45H82N12O14S2), with the sequence H-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH, belongs to the group of synthetic oligopeptides corresponding to a region of high amino-acid sequence similarity between uteroglobin and lipocortin I. The name 'antiflammins' is proposed for those peptides, which are valuable models for the development of novel anti-inflammatory agents of therapeutic importance. Anti-inflammatory peptide 1 possesses a potent anti-inflammatory activity in vivo and is a strong inhibitor of phospholipase A2 (PLA2), whose increased presence and activity results in inflammation and pain at certain bodily sites.

References:
1. Argiolas A, Pisano JJ (November 1983). "Facilitation of phospholipase A2 activity by mastoparans, a new class of mast cell degranulating peptides from wasp venom". J. Biol. Chem. 258 (22): 13697–702.

Chemical Properties

Cas No. 118850-71-8 SDF
Synonyms H2N-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH
Chemical Name Anti-Inflammatory Peptide 1
Canonical SMILES CC(C)CC(C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)O)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCSC)N
Formula C45H82N12O14S2 M.Wt 1079.33
Solubility ≥ 107.9mg/mL in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

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Review for Anti-Inflammatory Peptide 1

Average Rating: 5 ★★★★★ (Based on Reviews and 7 reference(s) in Google Scholar.)

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