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Anti-Inflammatory Peptide 1

Catalog No.GP10124

Anti-Inflammatory Peptide 1 Chemical Structure

PLA2 inhibitor

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Sample solution is provided at 25 µL, 10mM.

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Quality Control & SDS

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Anti-Inflammatory Peptide 1 (C45H82N12O14S2), with the sequence H-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH, belongs to the group of synthetic oligopeptides corresponding to a region of high amino-acid sequence similarity between uteroglobin and lipocortin I. The name 'antiflammins' is proposed for those peptides, which are valuable models for the development of novel anti-inflammatory agents of therapeutic importance. Anti-inflammatory peptide 1 possesses a potent anti-inflammatory activity in vivo and is a strong inhibitor of phospholipase A2 (PLA2), whose increased presence and activity results in inflammation and pain at certain bodily sites.

1. Argiolas A, Pisano JJ (November 1983). "Facilitation of phospholipase A2 activity by mastoparans, a new class of mast cell degranulating peptides from wasp venom". J. Biol. Chem. 258 (22): 13697–702.

Chemical Properties

Cas No. 118850-71-8 SDF
Synonyms H2N-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH
Chemical Name Anti-Inflammatory Peptide 1
Formula C45H82N12O14S2 M.Wt 1079.33
Solubility ≥ 107.9mg/mL in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

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Average Rating: 5 ★★★★★ (Based on Reviews and 7 reference(s) in Google Scholar.)

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