AZ2 |
| رقم الكتالوجGC62335 |
AZ2 هو مثبط PI3Kγ انتقائي للغاية (قيمة pIC50 لـ PI3Kγ هي 9.3)
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Cas No.: 2231760-33-9
Sample solution is provided at 25 µL, 10mM.
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AZ2 is a highly selective PI3Kγ inhibitor (The pIC50 value for PI3Kγ is 9.3). AZ2 can be used for the research of inflammatory and immune diseases[1].
AZ2 (0.1~100 nM; 1 hour; SKOV-3 cells) excellent selectivity for PI3Kγ is further confirmed with a constitutively activated PI3K/Akt pathway[1].
[1]. Gangadhara G, et al. A class of highly selective inhibitors bind to an active state of PI3Kγ. Nat Chem Biol. 2019;15(4):348-357.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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