الصفحة الرئيسية>>Signaling Pathways>> TGF-β / Smad Signaling>> PKC>>Bryostatin 3

Bryostatin 3

رقم الكتالوجGC12695

Bryostatin 3 ، وهو لاكتون كبير الحلقي ، هو منشط بروتين كيناز C ، مع Ki 2.75 نانومتريمكن أن يمنع Bryostatin 3 تثبيط 12-O-tetradecanoylphorbol-13-acetate (TPA) لتكاثر الخلايا ، ومع ذلك لم يمنع التصاق الطبقة السفلية للخلية المعززة بـ TPA

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Bryostatin 3 التركيب الكيميائي

Cas No.: 143370-84-7

الحجم السعر المخزون الكميّة
10μg
353٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Chemical Properties of Bryostatin 3

Cas No. 143370-84-7 SDF
Chemical Name
Canonical SMILES CC([C@@]1(O)[C@@H](OC(/C=C/C=C/CCC)=O)C([C@H]2[C@@H]3O1)=CC(O2)=O)(C)/C=C/[C@H](O[C@H](C[C@]4(O)O[C@H](C[C@@H](O)CC(O[C@@H]([C@H](O)C)C3)=O)C[C@H](OC(C)=O)C4(C)C)C/5)CC5=C/C(OC)=O
Formula C46H64O17 M.Wt 888.99
الذوبان Soluble in ethanol Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Bryostatin 3

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.1249 mL 5.6244 mL 11.2487 mL
5 mM 0.225 mL 1.1249 mL 2.2497 mL
10 mM 0.1125 mL 0.5624 mL 1.1249 mL
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** عند إعداد حلول المخزون، دائمًا استخدم الوزن الجزيئي الخاص بالدفعة للمنتج على ملصق القارورة MSDS / CoA (متوفر عبر الإنترنت).

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In vivo Formulation Calculator (Clear solution) of Bryostatin 3

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Bryostatin 3

Average Rating: 5 ★★★★★ (Based on Reviews and 2 reference(s) in Google Scholar.)

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