CMP-SiaNAz (CMP-NeuNAz) sodium is a sialic acid nucleotide sugar derivative. CMP-SiaNAz sodium is integrated into the glycosidic chain through the action of STs in the Golgi apparatus, forming SiaNAz substances. CMP-SiaNAz sodium can serve as a substrate for bacterial-derived sialic acid transferases and is used for chemical enzymatic labeling and imaging of cell surface glycosides [1] [2].
References:
[1]. Hong S, et al. Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification. Nat Commun. 2019 Apr 17;10(1):1799.
[2]. Martinez-Duncker I, et al. Towards in vivo imaging of cancer sialylation. Int J Mol Imaging. 2011;2011:283497.
References:
[1]. Hong S, et al. Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification. Nat Commun. 2019 Apr 17;10(1):1799.
[2]. Martinez-Duncker I, et al. Towards in vivo imaging of cancer sialylation. Int J Mol Imaging. 2011;2011:283497.