CP2 |
| رقم الكتالوجGC25304 |
CP2 is a cyclic peptide that inhibits the JmjC histone demethylases KDM4 with IC50 values of 42 nM and 29 nM for KDM4A and KDM4C, respectively.
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Cas No.: no CAS
Sample solution is provided at 25 µL, 10mM.
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CP2 is a cyclic peptide that inhibits the JmjC histone demethylases KDM4 with IC50 values of 42 nM and 29 nM for KDM4A and KDM4C, respectively.
CP2 uniquely binds in the KDM4A substrate-binding pocket. It binds differently to, but competes with, histone substrates in the active site[1].
[1] Akane Kawamura, et al. Nature Communications. 2017.
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