Angiotensin II (3-8), human |
| رقم الكتالوجGC35352 |
أنجيوتنسين 2 (3-8) ، الإنسان هو ناهض أقل فعالية لمستقبلات الأنجيوتنسين AT1
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Cas No.: 12676-15-2
Sample solution is provided at 25 µL, 10mM.
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Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor. Angiotensin AT1 receptor[1]
Human Angiotensin II (3-8) causes endothelium-dependent renal cortical vasodilatation, in anaesthetized rats. At doses up to 125 pmol/kg, human Angiotensin II (3-8) is without any cardiovascular effects, but with doses of 1.25 and 12.5 nmol/kg there are dose-dependent increases in mean arterial blood pressure and reductions in renal and mesenteric flows and vascular conductances[1].
[1]. Gardiner SM, et al. Regional haemodynamic effects of angiotensin II (3-8) in conscious rats. Br J Pharmacol. 1993 Sep;110(1):159-62.
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