Heraclenin |
| رقم الكتالوجGC36220 |
Heraclenin ، فورانوكومارين طبيعي ، يثبط بشكل كبير انتشار مستقبلات الخلايا التائية في الخلايا التائية الأولية البشرية بطريقة تعتمد على التركيز من خلال استهداف العامل النووي للخلايا التائية المنشطة (NFAT)
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Cas No.: 2880-49-1
Sample solution is provided at 25 µL, 10mM.
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Heraclenin, a natural furanocoumarin, isolated from the root parts of the plant Prangos pabularia. Heraclenin significantly inhibits T cell receptor-mediated proliferation in human primary T cells in a concentration-dependent manner by targeting nuclear factor of activated T-cells (NFAT)[1]. NFAT[1]
[1]. MÁrquez N, et al. Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT. Planta Med. 2004 Nov;70(11):1016-21.
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