Nicotinic acid mononucleotide (Synonyms: Deamido-NMN, NaMN, β-Nicotinic acid mononucleotide) |
| رقم الكتالوجGC36739 |
أحادي نيوكليوتيد حمض النيكوتينيك (NAMN) يتكون من حمض النيكوتينيك (NA) عبر حمض النيكوتينيك فسفوريبوزيل ترانسفيراز في التخليق الحيوي لـ NAD +
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Cas No.: 321-02-8
Sample solution is provided at 25 µL, 10mM.
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Nicotinic acid mononucleotide (NAMN) is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. Nicotinate mononucleotide is a substrate for nicotinamide mononucleotide/Nicotinic acid mononucleotide adenylyltransferase[1][2].
[1]. O'Hara JK, et al. Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum. PLoS One. 2014 Apr 18;9(4):e94061. [2]. Khan JA, et al. Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery. Expert Opin Ther Targets. 2007 May;11(5):695-705.
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