NLS PKKKRKV |
| رقم الكتالوجGC36750 |
NLS PKKKRKV هي إشارة توطين نووي (NLS) مشتقة من مستضد الورم الكبير 40 لفيروس القرد (مستضد SV40 كبير T). يمكن أن يعمل NLS PKKKRKV كطريقة لتعزيز الدخول النووي في مجال أبحاث نقل الجينات.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 95088-49-6
Sample solution is provided at 25 µL, 10mM.
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NLS (PKKKRKV) is a peptide derived from the simian virus 40 large tumor antigen (SV40 large T antigen), as a method to enhance nuclear entry in the field of gene transfer research[1][2].
[1]. Zanta MA, et al. Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):91-6. [2]. Cao S, et al. Enhanced effect of nuclear localization signal peptide during ultrasound-targeted microbubble destruction-mediated gene transfection. Mol Med Rep. 2017 Jul;16(1):565-572.
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