GLP-1 receptor agonist 15 (Example 4) is a GLP receptor agonist with an EC 50 of 0.74 nM. The IC50 for the hERG potassium ion channel is 10.1 μM. GLP-1 receptor agonist 15 can be used for research in the field of diabetes [1].
References:
[1]. Yang et al, Fused imidazole derivative, preparation method therefor, and medical use thereof, WO2022007979, US, 2021-09-01.
References:
[1]. Yang et al, Fused imidazole derivative, preparation method therefor, and medical use thereof, WO2022007979, US, 2021-09-01.