الصفحة الرئيسية>>Signaling Pathways>> Endocrinology and Hormones>> Smoothened Receptors>>IHR 1

IHR 1

رقم الكتالوجGC50201

IHR 1 عبارة عن مناهض Smo من غشاء الخلية غير منفذ للنافذة.

Products are for research use only. Not for human use. We do not sell to patients.

IHR 1 التركيب الكيميائي

Cas No.: 548779-60-8

الحجم السعر المخزون الكميّة
10 mg
215٫00
متوفر
50 mg
900٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro. Fluorescent Analog also available.

Fan et al (2014) The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation. Chem.Biol. 21 1680 PMID:25484239

مراجعات

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Average Rating: 5 ★★★★★ (Based on Reviews and 35 reference(s) in Google Scholar.)

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