Ingenol ((-)-Ingenol) |
| رقم الكتالوجGC32870 |
Ingenol ((-) - Ingenol) هو منشط PKC ، مع Ki 30 μ ؛ M ، مع نشاط مضاد للورم.
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Cas No.: 30220-46-3
Sample solution is provided at 25 µL, 10mM.
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Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity.
Ingenol is a PKC activator, with a Ki of 30 μM. Ingenol induces ornithine decarboxylase activity (1, 3 mM), and causes morphological changes (1 mM) in primary mouse epidermal keratinocytes. Ingenol (125 μM, 250 μM, 500 μM, 1 mM) also inhibits cell-cell communication[1].
[1]. Hasler CM, et al. Specific binding to protein kinase C by ingenol and its induction of biological responses. Cancer Res. 1992 Jan 1;52(1):202-8.
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