JD123 inhibits JNK1 activity and the expression of cJun (1-135). JD123 is a ATP-competitive p38-γ MAPK inhibitor, but not effect to ERK1, ERK2, or p38-α, p38-β or p38-δ. [1].
References:
[1]. Ngoei KR, et al. Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds. Biochim Biophys Acta. 2013;1834(6):1077-1088.
References:
[1]. Ngoei KR, et al. Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds. Biochim Biophys Acta. 2013;1834(6):1077-1088.