Methyl-2-bromo-LSD is a brain-penetrant 5-HT 2 receptor ligand. Methyl-2-bromo-LSD can be used for the research of alzheimer's disease, depression, schizophrenia, anxiety disorders [1].
In Vivo, Methyl-2-bromo-LSD (0.1 μg/kg; i.v.; single dose) (as the stable component of [11C]-MBL) selectively binds to serotonin 5-HT2 receptors in baboon brain[1].
References:
[1]. Wong DF, et al. Localization of serotonin 5-HT2 receptors in living human brain by positron emission tomography using N1-([11C]-methyl)-2-Br-LSD. Synapse. 1987;1(5):393-8.
In Vivo, Methyl-2-bromo-LSD (0.1 μg/kg; i.v.; single dose) (as the stable component of [11C]-MBL) selectively binds to serotonin 5-HT2 receptors in baboon brain[1].
References:
[1]. Wong DF, et al. Localization of serotonin 5-HT2 receptors in living human brain by positron emission tomography using N1-([11C]-methyl)-2-Br-LSD. Synapse. 1987;1(5):393-8.