Methyl oleanonate (Synonyms: 3-Oxoolean-12-en-28-oic acid methyl ester) |
رقم الكتالوجGC61055
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ميثيل أوليانونات هو ناهض ترايتيربين طبيعي PPARγ معزول عن أنواع البستاشياميثيل أوليانونات هو أحد مشتقات حمض الأولينوليك المعدلة مع تأثيرات مضادة للسرطان
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1721-58-0
Sample solution is provided at 25 µL, 10mM.
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Methyl oleanonate is a natural triterpene PPARγ agonist isolated from the species of Pistacia[1]. Methyl oleanonate is a modified oleanolic acid derivative with anti-cancer effects[2].
[1]. Rasmus K Petersen, et al. Pharmacophore-driven identification of PPARγ agonists from natural sources. J Comput Aided Mol Des. 2011 Feb;25(2):107-16. [2]. Barbara Bednarczyk-Cwynar, et al. Anticancer effect of A-ring or/and C-ring modified oleanolic acid derivatives on KB, MCF-7 and HeLa cell lines. Org Biomol Chem. 2012 Mar 21;10(11):2201-5
| Cas No. | 1721-58-0 | SDF | |
| المرادفات | 3-Oxoolean-12-en-28-oic acid methyl ester | ||
| Canonical SMILES | CC1(C)C(CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])CC(C)(C)CC[C@@](C(OC)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H])=O | ||
| Formula | C31H48O3 | M.Wt | 468.71 |
| الذوبان | Storage | Store at -20°C | |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 2.1335 mL | 10.6676 mL | 21.3352 mL |
| 5 mM | 426.7 μL | 2.1335 mL | 4.267 mL |
| 10 mM | 213.4 μL | 1.0668 mL | 2.1335 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)