β,β-Dimethylacrylshikonin |
| رقم الكتالوجGC37982 |
β ؛ ، β ؛ -Dimethylacrylshikonin (Isoarnebin I) هو مشتق من naphthoquinone معزول عن Arnebia nobilis ، ويعزز تكوين الأوعية عن طريق تحفيز تعبير eNOS و VEGF و HIF-1α من خلال 2211.22246 المعتمد على HIF-1α نشاط.
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Cas No.: 24502-79-2
Sample solution is provided at 25 µL, 10mM.
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β,β-Dimethylacrylshikonin is a naphthoquinone derivative isolated from Arnebia nobilis, promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. Arnebin 1 has anti-tumor activity[1].
[1]. Zeng Z, et al. Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. Int J Mol Med. 2015 Sep;36(3):685-97. [2]. Sidhu GS, et al. Arnebin-1 accelerates normal and hydrocortisone-induced impaired wound healing. J Invest Dermatol. 1999 Nov;113(5):773-81.
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