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Pseurotin A (Synonyms: NSC 348694)

رقم الكتالوجGC18459 Copy One-Click Copy Product Info

Pseurotin A ، مستقلب ثانوي من Aspergillus والفطريات الأخرى ، هو مثبط تنافسي لـ chitin synthase وعامل عصبيPseurotin A يثبط إنتاج IgE (IC = 3.6 ميكرومتر)نشاط انتيتومور

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Pseurotin A التركيب الكيميائي

Cas No.: 58523-30-1

الحجم السعر المخزون الكميّة
1mg
156٫00
متوفر
5mg
502٫00
متوفر

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مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Description of Pseurotin A

Pseurotin A is a secondary metabolite produced by Aspergillus and other fungi. Its expression is induced in response to hypoxia. Pseurotin A is a secondary metabolite produced by Aspergillus and other fungi. Its expression is induced in response to hypoxia. Pseurotin A has been shown to inhibit IgE production by mouse B cells in culture (IC50 = 3.6 μM) and dose-dependently (0.4-25 μg/ml) stimulate neuritogenic activity in rat pheochromocytoma PC12 cells. It also demonstrates nematicidal activity at 300 μg/ml.

Chemical Properties of Pseurotin A

Cas No. 58523-30-1 SDF
المرادفات NSC 348694
Chemical Name (5S)-8S-benzoyl-2-[1S,2S-dihydroxy-3Z-hexen-1-yl]-9R-hydroxy-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione
Canonical SMILES O=C1N[C@](C(C2=CC=CC=C2)=O)(OC)[C@H](O)[C@@]31C(C(C)=C([C@@H](O)[C@@H](O)/C=C\CC)O3)=O
Formula C22H25NO8 M.Wt 431.4
الذوبان Methanol: Soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Pseurotin A

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.318 mL 11.5902 mL 23.1803 mL
5 mM 463.6 μL 2.318 mL 4.6361 mL
10 mM 231.8 μL 1.159 mL 2.318 mL
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In vivo Formulation Calculator (Clear solution) of Pseurotin A

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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