(R)-Viloxazine-d 5 hydrochloride ((R)-Viloxazin-d 5 hydrochloride; (R)-Emovit-d 5 hydrochloride) is the deuterated-labeled (R)-Viloxazine hydrochloride. (R)-Viloxazine hydrochloride is the less active R-isomer of Viloxazine hydrochloride. (R)-Viloxazine hydrochloride can be used in the research of depression [1] [2].
References:
[1]. Howe R, et al. Optical isomers of 2-(2-ethoxyphenoxymethyl)tetrahydro-1,4-oxazine (viloxazine) and related compounds. Journal of medicinal chemistry. 1976 Aug;19(8):1074.
[2]. Blackburn TP, et al. Effects of viloxazine, its optical isomers and its major metabolites on biogenic amine uptake mechanisms in vitro and in vivo. European journal of pharmacology. 1978 Dec 01;52(3-4):367-74.
References:
[1]. Howe R, et al. Optical isomers of 2-(2-ethoxyphenoxymethyl)tetrahydro-1,4-oxazine (viloxazine) and related compounds. Journal of medicinal chemistry. 1976 Aug;19(8):1074.
[2]. Blackburn TP, et al. Effects of viloxazine, its optical isomers and its major metabolites on biogenic amine uptake mechanisms in vitro and in vivo. European journal of pharmacology. 1978 Dec 01;52(3-4):367-74.