Obesity, Appetite Control & Diabetes
Obesity, Appetite Control & Diabetes
Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions.
Stephen M. Stahl, M.D., Ph.D. read more
Research Areas
Products Related to Obesity, Appetite Control & Diabetes(354)
- GC44518Osteocalcin (1-49) (human) (trifluoroacetate salt)CAS: 136461-80-8Purity: >95.00%
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone.
- GC44524Oxyntomodulin (bovine, porcine) (trifluoroacetate salt)Purity: >95.00%
Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut.
- GC44544Palmitoleic Acid (sodium salt)CAS: 6610-24-8Purity: >95.00%
Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue.
- GC44598Peptide YY (human) (trifluoroacetate salt)Purity: >95.00%
Peptide YY (human) (trifluoroacetate salt) is a peptide hormone secreted by intestinal L cells.
- GC44645Pioglitazone (potassium salt)CAS: 1266523-09-4Purity: >98.00%
Pioglitazone (U 72107) البوتاسيوم هو PPARγ نشط عن طريق الفم وانتقائي ؛ ناهض (مستقبلات منشط بالبيروكسيسوم) مع تقارب عالٍ ملزم بـ PPARγ ؛ مجال ربط يجند مع EC50 من 0.93 μ ؛ M و 0.99 μ ؛ M للإنسان والفأر PPARγ ؛ ، على التوالي.
- GC44660PlatensimycinCAS: 835876-32-9Purity: >95.00%
Platensimycin (PTM) is an antibiotic produced by S.
- GC44775PTP1B InhibitorCAS: 765317-72-4Purity: >98.00%
مثبط PTP1B هو مثبط خيفي غير تنافسي لبروتين التيروزين فوسفاتيز PTP1B ، مع IC50 من 8 μ ؛ M.
- GC44811Remogliflozin etabonateCAS: 442201-24-3Purity: >99.00%
Remogliflozin etabonate (GSK189075) هو مثبط نشط عن طريق الفم وانتقائي ومنخفض التقارب لجلوكوز الصوديوم (SGLT2) بقيم Ki تبلغ 1.95 ميكرومتر ، 2.14 ميكرومتر ، 43.1 ميكرومتر ، 8.57 ميكرومتر لـ hSGLT2 ، rSGLT1 ، rSGLT1 ، على التوالي
- GC44851Rosiglitazone (potassium salt)CAS: 316371-84-3Purity: >98.00%
البوتاسيوم Rosiglitazone (BRL 49653) هو مادة انتقائية فعالة عن طريق الفم PPARγ ؛ ناهض (EC50: 60 نانومتر ، Kd: 40 نانومتر).
- GC44895Sitagliptin N-Sulfate (sodium salt)CAS: 2470126-25-9Purity: >95.00%
Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
- GC44914Somatostatin-14 (acetate)CAS: 54472-66-1Purity: >98.00%
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin.
- GC45139Vapreotide (trifluoroacetate salt)Purity: >95.00%
Vapreotide is a peptide neurokinin-1 receptor (NK1) antagonist and analog of somatostatin (IC50 = 330 nM in a radioligand binding assay).
- GC45144Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)CAS: 565453-41-0Purity: >98.00%
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans.
- GC45186ZLN005 (hydrochloride)Purity: >98.00%
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis.
- GC45252(-)-Sitagliptin Carbamoyl GlucuronideCAS: 940002-59-5Purity: >90.00%
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC44518 | Osteocalcin (1-49) (human) (trifluoroacetate salt) | 136461-80-8 | >95.00% | |
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. | ||||
| GC44524 | Oxyntomodulin (bovine, porcine) (trifluoroacetate salt) | - | >95.00% | |
Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut. | ||||
| GC44529 | P053 | 2748196-63-4 | >97.00% | |
P053 هو مثبط سيراميد سينسيز 1 (CerS1) قوي وغير تنافسي وانتقائي مع IC50 بمقدار 0.5 ميكرومتر | ||||
| GC44544 | Palmitoleic Acid (sodium salt) | 6610-24-8 | >95.00% | |
Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue. | ||||
| GC44598 | Peptide YY (human) (trifluoroacetate salt) | - | >95.00% | |
Peptide YY (human) (trifluoroacetate salt) is a peptide hormone secreted by intestinal L cells. | ||||
| GC44645 | Pioglitazone (potassium salt) | 1266523-09-4 | >98.00% | |
Pioglitazone (U 72107) البوتاسيوم هو PPARγ نشط عن طريق الفم وانتقائي ؛ ناهض (مستقبلات منشط بالبيروكسيسوم) مع تقارب عالٍ ملزم بـ PPARγ ؛ مجال ربط يجند مع EC50 من 0.93 μ ؛ M و 0.99 μ ؛ M للإنسان والفأر PPARγ ؛ ، على التوالي. | ||||
| GC44660 | Platensimycin | 835876-32-9 | >95.00% | |
Platensimycin (PTM) is an antibiotic produced by S. | ||||
| GC44775 | PTP1B Inhibitor | 765317-72-4 | >98.00% | |
مثبط PTP1B هو مثبط خيفي غير تنافسي لبروتين التيروزين فوسفاتيز PTP1B ، مع IC50 من 8 μ ؛ M. | ||||
| GC44811 | Remogliflozin etabonate | 442201-24-3 | >99.00% | |
Remogliflozin etabonate (GSK189075) هو مثبط نشط عن طريق الفم وانتقائي ومنخفض التقارب لجلوكوز الصوديوم (SGLT2) بقيم Ki تبلغ 1.95 ميكرومتر ، 2.14 ميكرومتر ، 43.1 ميكرومتر ، 8.57 ميكرومتر لـ hSGLT2 ، rSGLT1 ، rSGLT1 ، على التوالي | ||||
| GC44851 | Rosiglitazone (potassium salt) | 316371-84-3 | >98.00% | |
البوتاسيوم Rosiglitazone (BRL 49653) هو مادة انتقائية فعالة عن طريق الفم PPARγ ؛ ناهض (EC50: 60 نانومتر ، Kd: 40 نانومتر). | ||||
| GC44895 | Sitagliptin N-Sulfate (sodium salt) | 2470126-25-9 | >95.00% | |
Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. | ||||
| GC44914 | Somatostatin-14 (acetate) | 54472-66-1 | >98.00% | |
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. | ||||
| GC44954 | Stevioside (hydrate) | - | >95.00% | |
Stevioside is a natural non-caloric sweetener. | ||||
| GC45139 | Vapreotide (trifluoroacetate salt) | - | >95.00% | |
Vapreotide is a peptide neurokinin-1 receptor (NK1) antagonist and analog of somatostatin (IC50 = 330 nM in a radioligand binding assay). | ||||
| GC45144 | Vildagliptin carboxylic acid metabolite (trifluoroacetate salt) | 565453-41-0 | >98.00% | |
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. | ||||
| GC45164 | WWL229 | 1338575-28-2 | >98.00% | |
WWL229 هو مثبط انتقائي للكربوكسيل استيراز 3 (Ces3) مع IC50 من 1.94 ميكرومتر | ||||
| GC45186 | ZLN005 (hydrochloride) | - | >98.00% | |
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis. | ||||
| GC45252 | (-)-Sitagliptin Carbamoyl Glucuronide | 940002-59-5 | >90.00% | |
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. | ||||
| GC45277 | (±)-Camphene | 79-92-5 | >99.50% | |
| ||||
| GC45315 | 1-Palmitoyl-d9-2,3-Dipalmitoyl-sn-glycerol | 2738376-70-8 | >99.00% | |
| ||||
| GC45320 | 1-Stearoyl-3-Oleoyl-rac-glycerol | 18266-27-8 | >98.00% | |
| ||||
| GC45379 | Alloxan (hydrate) | 2244-11-3 | >98.00% | |
| ||||
| GC45490 | Kisspeptin-54 (human) (trifluoroacetate salt) | - | >95.00% | |
| ||||
| GC45506 | MD001 | 2254605-76-8 | >90.00% | |
| ||||