Drug Metabolite

Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen.

Acetaminophen sulfate is a metabolite of acetaminophen.

all-trans Retinoyl β-D-glucuronide is a metabolite of all-trans retinoic acid formed by the UDP-glucuronosyltransferase (UGT) system.

Avanafil metabolite M16 is a major inactive metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil.

Avanafil metabolite M4 is a major active metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil.

Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib.

Benazeprilat نشط عن طريق الفم ومستقلب نشط من benazepril ، مثبط ACE المحتوي على الكربوكسيل مع نشاط خافض للضغط

ثاني كبريتيد الكابتوبريل هو مستقلب لكابتوبريل مع نشاط خافض للضغط

Celecoxib carboxylic acid acyl-β-D-glucuronide is a phase II metabolite of celecoxib.

Chlorzoxazone N-glucuronide is a phase II metabolite of the skeletal muscle relaxant chlorzoxazone.

Clindamycin sulfoxide is an active metabolite of the antibiotic clindamycin.

Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM).

Clozapine N-oxide is a major metabolite of clozapine and an activator of designer receptors exclusively activated by designer drugs (DREADDs) derived from human muscarinic acetylcholine receptors (EC50s = 16.7, 323, 17.4, 18.3, and 18.7 nM for PASMCs expressing hM1-5D receptors, respectively).

Cyclo(L-Tyr-L-Val) is a diketopiperazine secondary fungal metabolite originally isolated from N.

Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran.

Dapagliflozin-3-O-β-D-glucuronide is a metabolite of dapagliflozin.

Dehydro aripiprazole is the primary, active metabolite of aripiprazole, an atypical antipsychotic.

Dehydro nifedipine is an active metabolite of nifedipine, a calcium channel blocker present in formulations used to treat hypertension and angina.

Desacetyl bisacodyl (DAB) is an active metabolite of two stimulant laxatives, bisacodyl and sodium picosulfate.

Desethylene ciprofloxacin is a major metabolite of ciprofloxacin.

Desmethyl Erlotinib (OSI-420 free base) هو مستقلب نشط من Erlotinibإرلوتينيب هو مثبط قوي لتيروزين كيناز EGFR

ديسميثيلدوكسيبين (هيدروكلوريد) هو المستقلب الرئيسي لدوكسيبين.

Paroxetine is a potent, selective serotonin reuptake inhibitor (Ki = 0.72 nM) that has been used in cases of depression and anxiety disorder.

Diclofenac acyl-β-D-glucuronide is an active metabolite of diclofenac and the predominant metabolite in rat.